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NBME 24 Answers

nbme24/Block 2/Question#9 (57.3 difficulty score)
In which of the following stages of the cell ...
tags: cell_bio 

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submitted by snoodle(23),

just wanted to add that questions that ask small details like this make me want to carve my eyeballs out

j44n  This is the shit that keeps me up at night +2  

submitted by madojo(176),
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rothnAe awy ot think ubota ihts is tashw het elsocs gteas ot imtssoi bcesaeu rtghi ebrefo M s(om)isti yuo eedn to heav icttimo slyincc deeiyhsnzts, nad htat douwl be 2G

G1 -t&-g; S --;t&g G2 t&-;g- M

submitted by sweetmed(144),
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cCnily DA,,E dan ofr 1G ot S ntoitrsina md[ea ni .G]1 nyilcC B si orf 2G ot M dne[smaoantirit ni G2.]

mousie +3  
fahmed14  Cyclins help regulate cell cycle phases. They help with checkpoints before progression to the next phase of a cell cycle. Therefore the checkpoint before mitosis would be in G2 and probably where mitotic specific cyclins are synthesized +11  
artist90 . 4 types of Cyclins and when they rise and fall. +2  

submitted by nerdstewiegriffin(34),

G1 checkpoint: Cyclin D/CDK4 complex with p53 and rb G2 checkpoint: Cyclin B and CDK 1

Way to remember: G1 is associated with higher numbers D and 4 G2 is associated with B and 1


and also F@CK me and F@CK NBME!!!

snripper  But the question doesn't mention anything about which cyclin. How does this help? +1  
thyenman  @snripper I think the word choice of "mitotic cyclins" is suppose to show they wanted cyclin B which is produced in G2. This resource specifically refers to cyclin B with mitosis. CDKs and different cyclins are expressed at different stages of the cell cycle: cyclin D (G1), cyclin E (G1/S), cyclin A (S), cyclin B (mitosis). - +1