NRTIs are the main HIV therapy drug that can cause bone marrow suppression (not as common with NNRTIs). This class includes zidovudine, didanosine, emtricitabine, lamivudine, stavudine, abacavir. Zidovudine is most known for this side effect.
Nelfinavir = protease inhibitor
azithromycin = aminoglycoside (not really used for HIV)
pentamidine = another antimicrobial, mostly used for pneumocystis I think?
Lamivudine = another NRTI but less known for bone marrow suppression
adisdiadochokineticAzithromycin is a macrolide, not an aminoglycoside FYI, and its use in HIV is primarily as prophylaxis at very low CD4 counts for, among other things, the mycobacterium avium complex. +8
nbmehelpHow would we have known to choose Zidovudine over Lamivudine tho+5
mjmejora@nbmehelp the sketchy with Princess Izolde (Zidovudine) eating bone marrow was my only tip off+8
niboonshyou have ero bone marrow if you take idovudine +1
niboonshthe z's were supposed to be bold idk what happened.
you have Zero bone marrow if you take Zidovudine +5
t123Zidovudine is also a very early NRTI developed. As a good rule of thumb, older drugs have worse side effects+2
submitted by โneonem(630)
NRTIs are the main HIV therapy drug that can cause bone marrow suppression (not as common with NNRTIs). This class includes zidovudine, didanosine, emtricitabine, lamivudine, stavudine, abacavir. Zidovudine is most known for this side effect.
Nelfinavir = protease inhibitor azithromycin = aminoglycoside (not really used for HIV) pentamidine = another antimicrobial, mostly used for pneumocystis I think? Lamivudine = another NRTI but less known for bone marrow suppression