NBME 24 Probenecid (NBME Answers)

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Retired NBME 24 Answers

nbme24/Block 2/Question#24 (reveal difficulty score)
A 59-year-old man has repeated episodes of ...
Probenecid 🔍 / 📺 / 🌳 / 📖
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+4 upvote downvote
submitted by ∗lsmarshall(465)

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"Probenecid and high-dose salicylates inhibit reabsorption of uric acid in proximal convoluted tubule (also inhibits secretion of penicillin)." - First Aid 2019

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uslme123 so ............... +12

adisdiadochokinetic So probenecid is the best answer here because they only specified acetylsalicylic acid, not the dosage, and low-dose acetylsalicylic acid has the opposite effect. +9

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submitted by ∗niboonsh(409)

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Probenecid makes you Pee

Colchicine clenches your microtubules

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+0 upvote downvote
submitted by ∗unknown001(9)

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i have never herd acetylsalicylic being prescribed for gout, and i practiced for a couple of years.

so think simple, choose probenicid since its a fairly known drug in the gout world, and enjoy your 250 on step 1

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