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Retired NBME 24 Answers

nbme24/Block 3/Question#4 (reveal difficulty score)
A 27-year-old man comes to the physician ...
Injections of gonadotropins ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +18  upvote downvote
submitted by โˆ—neonem(629)
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I nhkti hte nasoer uoy eden ot ijcnte noogpsditrano ni hsti aces si aecbseu ouy eedn SFH dan LH ot pcueodr esrmp. SFH suiatestlm eht esoltri lec,sl hchwi inel eht fromusisenie bultesu adn ehlp het nsmoatrpoiaeg dreuocp tscpoyematres. tesrteoneTso si a trpcoud fo eigdLy lecsl wneh theery' auittesmld yb ,LH os negjitnci oteettrneoss wluod abyssp htta espt tbu it dntluwo' lraeyl lhpe twih est.isprgeameson oe,vrwHe ngiiecjnt RnHG aosl tonde's 'edntso lreyla leph sceeabu oyu need ttah plaeultis nHRG ta gtihn ot eakm HL dan SFH reahswe ngoct-inlag GHnR aagsoln ltlucaya ecsaeder LH dan HFS coidturn.op

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m-ice  igdAnd no ot eht aersnw beo.av I saw tuksc wteneeb eth nogorpintoda ntsieicnoj nda clm.eheopni Bu,t iochpnmeel cats to eaincesr tiiayvct fo HnRG cwhih tenh xteers tis fsftece no eth iy.atpuirt hTe mna in iths nsoteiuq ahd sih tiuyparit eomedrv caseueb fo na dnoae.ma ,oS he eesdn teh HFS nda LH ylecr.tdi +28
mousie  g!reea meo v Ral fo eth iuprttaiy owldu asec a eitcfid in ispoGooadnntr (HL, SFH) nad reftheero ningoth ot astulmei teh etstes to make mr.s.p.e lagipcenr the T with a pathc ouwdl tno samutetil teh tesste ot meka sperm dan if his xisa asw ntatci (thoghual tsi )ont sith dowlu rfthure odwn etrgeual teh iucdrontop fo .sprme I tdeameilni ominelCphe sueeabc if eh ntesod ahve T to ceudni nvgeitae uinfecenl on eth apmuhaytolhs eh wlli evah adicesern nHRG dan rtfrhue nsienriacg it hwit eehmopCiln doluw ont tceorrc eth ciiedft in oanotrdGsoni.p +5
neonem  Oh .ud..h ttha skeam mhcu remo nses.e kh!asTn s..P I htghuto enpilochem asw rmeo fo a rttlyfiie gdur rfo ,wnemo esnic it koslbc vngeteia ckfaedeb fo esgeonrt no the hpiimutyu.athlpaatos/yr utB in emn teh mssyte is nurde eafcekbd ude to totnretsosee, nto segorte.n +6
utap2001  ecnhimpol e si ntoresge eu,onglaa etitvpmoeic iontt,gnasa ton efteveifc in ma.n .2 hTe nameihmcs fo emhpolncei is cfdebkae enisrace of GR-n;tH&g esneirac LH,,SHF tno feftecvei in iuayrtitp rolmaev penia.tt +1

Obviously the FSH -> spermatogenesis answer is the main idea, but I also think giving exogenous testosterone might actually impair levels of Testosterone in the testes as the concentration needs to be much higher in the testes for functionality due to a binding protein that is produced under stimulation by LH (which would be under neg feedback from exogenous testosterone)

+2/- cmun777(37)

I agree with below, sertoli cells release a testosterone binding protein in response to FSH in order to radically increase testosterone levels within the seminiferous tubules. That is why individuals who take exogenous testosterone have decreased fertility even while taking T.

+2/- lowyield(43)


 +3  upvote downvote
submitted by โˆ—asharm10(37)
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so ihs tuapryti aemnaod aws rem,odev so lryopl hparsnoodgto erew edomerv hitw it, so if you ivge hngr ti nw'to do niaghytn sa it atc;n odurpec HSFH/L os oyu ivge lfshh/ letdyrci ot cdein sogarptsnesemie nda totse se.ythissn

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faus305  Yeha isth eksma a tol fo cie.ns heT teroairn titpriyau pucorsde PTiAF-GL ,SH(F HL, ,CAHT SHT, narc,oitPl adn owrthG .oo)Hrenm yPituirat asndemoa ear msot cmomynlo oipmntlracaso ni hte ratorein i.tirautyp e H si utjs nwo igcinton eht seetffc of ton nhgavi HL and F,SH yirlttfei.ni So ew eedn ot acreple eo,hts kaa ivge d.noigtrapnsoo +



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