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Retired NBME 24 Answers

nbme24/Block 3/Question#4 (reveal difficulty score)
A 27-year-old man comes to the physician ...
Injections of gonadotropins ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +18  upvote downvote
submitted by โˆ—neonem(629)
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I tinkh eht senoar you eden ot njtiec ingnstdopaoor in iths easc si aecuebs uoy edne SHF adn HL ot cpoedur ep.rms HSF ssteaimlut teh eostlri e,lcls iwhhc nile teh ousefsirneim bstuelu adn leph het repaongmiatos edcupro ysmaptoecse.rt setnreosoTet is a rtduopc of eLdygi cslel nwhe 'ehyrte idlatustem by LH, os ninietjcg setesnrottoe dlowu aspsby ahtt step tbu it ndlwt'ou arleyl phle hitw gsntesmsarp.oeei oe,evrwH jtiginnce nRGH loas edos'tn sotne'd leayrl phel useaceb you dene tath uealtlips HnGR at gitnh ot amke HL nda FHS hrwaees -nlgtiogacn nGRH salgoan ytacllau reaseedc HL nad FSH porc.unotdi

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m-ice  diAdgn on to eth nwraes aovbe. I aws cuskt wbeenet the pioagnorntod joicsntnei and enep.ihmcol tu,B eopcmlneih tsac to ireacnse ittcavyi fo RnGH hwhci neth etsexr tsi tcsefef no eht atuirpy.it Teh nam ni this eqnosuti dha hsi autirtyip evdeorm cebeuas of na mnoda.ea ,So he eesnd het FHS adn LH l.rceidyt +28
mousie  rgeea! lmR evoa of eth yituaitpr wdlou asce a tiefdci in iGonnptrdoosa (H,L SFH) dan otrhefree nothngi to aitlmsue teh sttees to kmea es.rpm.. lpgincare eht T whti a ahctp dulwo ton ltausteim het sestet ot eakm rsemp dan fi sih asxi aws ttncia ol(uhahgt tsi not) tshi ouldw urtrhfe dwon argeltue the ndootpucir fo re.mps I lieedmaint eliemCnpho ubescae fi he dnsote eahv T ot iendcu ngeatevi lfineucen on het yahpthaolmus he llwi ehav anreisecd nHGR dan rethruf sigincnrae it ihtw mehlnipCeo ludow not rterocc the fcitide ni rt.onGoioandsp +5
neonem  hO dh.u.. tath kseam cuhm meor sense. Tsknha! s..P I hgoutth pcimlonehe was rmoe fo a titlefiyr gdur fro m,oenw scnie ti klbsoc veinteag feekdcba fo enrsoget no hte ia.riu/psalthhmupayotyt But ni nem eth esmyts si rednu cefkbeda ude to t,sertoonetse ont ng.soeert +6
utap2001  oclem phnei is reetgnos l,uoganae teiioevtpmc tanntois,ga tno vtceeeiff ni n.am .2 The cmnheaism fo lemihpneco si feadcekb nseracie of -nH&;RgGt siercnae ,H,SLHF otn feevftcei ni yruiptait oavrmel pit.tena +1

Obviously the FSH -> spermatogenesis answer is the main idea, but I also think giving exogenous testosterone might actually impair levels of Testosterone in the testes as the concentration needs to be much higher in the testes for functionality due to a binding protein that is produced under stimulation by LH (which would be under neg feedback from exogenous testosterone)

+2/- cmun777(37)

I agree with below, sertoli cells release a testosterone binding protein in response to FSH in order to radically increase testosterone levels within the seminiferous tubules. That is why individuals who take exogenous testosterone have decreased fertility even while taking T.

+2/- lowyield(43)

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 +3  upvote downvote
submitted by โˆ—asharm10(37)
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so ihs ttiapuyr aadnoem wsa morev,ed so lrlypo adpsgtnorhoo rwee moerdve htiw ,ti os if uyo vieg nghr it wtn'o do ntghyain sa it tnca; odpceur FHL/SH os ouy vieg f/hhsl litrcdey to cndei gpesstemasnieor dna seott s.iehnsyts

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faus305  eYah hsit mksea a lto of .sneic heT tarirnoe ytpiaiurt duespcro TiFPLA-G (HF,S L,H T,CHA HT,S ,cnParoitl dan rohGwt orH.n)eom ityatPrui dasaeonm rea ostm oylmomcn napomoclartsi in eht riotnrea iyttrapui. eH is tjus wno iiontcng het cesftfe fo otn ivahgn LH adn ,HSF .niyfiltetri oS we deen ot pralcee hsot,e aak gvei p.ngodstioroan +


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