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Retired NBME 24 Answers

nbme24/Block 3/Question#4 (reveal difficulty score)
A 27-year-old man comes to the physician ...
Injections of gonadotropins ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +18  upvote downvote
submitted by โˆ—neonem(630)
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I hiktn eht anoers uyo edne to jitcen dtonigonpsaor in sith aecs si aeceubs you deen HFS dan LH to ocpured .mespr SFH ttsamielus eht loestir ,slelc ichhw enli hte ueiismfsorne sbelutu nad phel eth rmgatpnoaesio docrepu rcsse.eattpymo eresTntsoeto si a rcodptu fo ygeiLd lescl when ty'ehre umitatdels yb H,L so itcjeginn toenretstsoe udlow ypssba atht stpe but it odnwt'ul laeylr pelh tihw see.astiogpmrnse vwr,Heoe cijentngi RnHG aosl dteons' eosdn't eyarll lphe aceuebs oyu ende hatt ulpitelas RHnG at nihtg to ekam HL dan HSF reeshwa lggcitonn-a nHRG nlaagso ulatclay arsecede HL dan HSF pitun.oordc

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m-ice  dgidAn no ot het rnswea veb.oa I swa skutc etenebw eth rtpoonoingda ijcseintno dna enc.leohpmi tu,B nhiempoecl tsac to ircnesea yitciatv of RnHG hhcwi nhet exerst ist eesffct on hte tiuatp.ryi ehT man in tshi nsqtouie dha his iaruittyp evoermd eacusbe fo an ondamae. ,oS he esedn eth SFH and LH yictdl.er +28
mousie  a!reeg e mRav ol of eht tiiyrtuap wdolu ceas a cifited in onoGtnopidrsa ,LH( HSF) dan errfoehet tinohng ot miatulse het testse ot mkea .mr.esp. crniagpel het T hiwt a apcht dulow otn lteamtius teh tsetse to ekma mpser dan if ihs asix saw tcitna hhotal(gu sti n)to tsih luodw rhufert ondw taeulger eht onoritudcp of sp.mer I anilmieetd mCphoenlie ecbesau if eh nsoetd eahv T to cdunie agvtieen ncuflenei on eth smhahytoplua he iwll ahev ecndasier GHRn and feurrth grnniasiec ti whit emeChonlip uolwd otn ccetror the dictfie in andonoostrG.ip +5
neonem  hO uh..d. taht easmk hcum orme .eenss h!anskT ..sP I gthhuto pmlnechoei swa reom of a rfitlteyi drug ofr wno,em ecnis it kslobc intgvaee ckefadeb of oergetsn no eth aoiih/.lhuuytmytastarpp But ni nme hte estmys si enudr kbdeafec due to tsteneroote,s nto ereo.sngt +6
utap2001  oicnple ehm si orneegst aouleang, eitvtipmeco nonia,ttsga nto ciefeetvf ni .anm .2 Teh snmaecmih fo eoihmnclep si ckfeabed nraeiesc of -&;HRtnGg ceisraen ,,HFSHL ton eifvfetce ni yapiuirtt mevaolr ae.nittp +1

Obviously the FSH -> spermatogenesis answer is the main idea, but I also think giving exogenous testosterone might actually impair levels of Testosterone in the testes as the concentration needs to be much higher in the testes for functionality due to a binding protein that is produced under stimulation by LH (which would be under neg feedback from exogenous testosterone)

+2/- cmun777(37)

I agree with below, sertoli cells release a testosterone binding protein in response to FSH in order to radically increase testosterone levels within the seminiferous tubules. That is why individuals who take exogenous testosterone have decreased fertility even while taking T.

+2/- lowyield(43)

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 +3  upvote downvote
submitted by โˆ—asharm10(37)
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so his ttiaypru aemanod wsa ,droeemv os rloply dhgsaportono ewer ervdeom ithw ti, os if ouy iveg hgrn it ot'wn do ntyangih sa ti nct;a rueopdc F/HHSL so uyo vieg hshlf/ ircyedtl to ceind apsstgireoneems and ttoes yensshti.s

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faus305  aYhe tsih kemsa a tol fo e.insc Teh aeorrint tptuiyira csueoprd iF-TPGLA FS(H, H,L TCHA, S,TH r,tlcaPino adn wGohrt eooHn).mr tiaytriPu dsmaoaen rae stmo mnycmloo rtosialcompna ni het ritareno ta.iipyurt eH is utjs nwo oitnigcn eth cefstef of tno vinagh LH dan ,SHF yetiflni.tri So we ened ot pcaleer ,sehto aka egiv poarodstinn.og +


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