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Retired NBME 24 Answers

nbme24/Block 3/Question#4 (reveal difficulty score)
A 27-year-old man comes to the physician ...
Injections of gonadotropins ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +18  upvote downvote
submitted by โˆ—neonem(629)
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I nihtk eht orsane yuo dene to ntjice anroindgootsp ni ihst sace is asbceeu yuo ened SHF nad LH to pocudre emr.sp HSF mitsutleas eth slrteoi lsc,el hichw ieln hte infemeirusos tuselub dna hepl the atpemnrogsoai pecdruo tteae.rspcosmy sTntterooees si a otupdcr of gLidey lselc ehnw eyerht' tetsaidlum yb H,L os iijctngne rteteeosntos dwolu yasbsp htat step btu ti t'dlonwu laeyrl ephl hiwt m.snostaeseiregp Hwrv,oee jtiecnnig nHRG loas doesnt' oed'snt rlyela hepl caeseub yuo eedn htat upsliatel HnRG ta ihtgn ot kaem LH nda SHF ewehsar nagcglniot- nHGR naaolsg tulaalcy eareecds HL dna HSF uiotdr.ocpn

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m-ice  dnAigd on ot het wnesra aebv.o I wsa usckt eeenwtb teh notadgroionp onnitjsiec dan in.hmeeclop B,tu nelhemoipc scat ot ceesnair yvtciita fo GHnR whhci then etsrex tis ftcesef no the t.aiyitupr The mna in ihts qeuonist dah ish iutaprity odrmeev busceea of an edoaman. So, eh esdne eht SHF and HL dl.ericty +28
mousie  eea!rg ave omlR fo hte turiitypa uwodl ceas a ticifde ni rpaosdontonGi L(H, FSH) nad eofterreh gohintn ot lusiamte eht sttese to ekma mrs...pe rlpiagnec het T iwht a pthca wdolu not eusmaltit hte ststee to kema repsm adn if hsi sxai aws atitcn hglaouht( sit o)tn sthi uldwo rrhtfue ndwo aleeurtg eth ouptdnirco fo s.empr I leeiaditmn eplCnmiohe sceuabe fi eh etndos avhe T to uncedi vinegeta enicnluef on hte otsamyhulaph he llwi heva daeecnsir HGRn adn feruhtr encnriisag it wiht nipoChelme ulwdo ont rctocer the icdeift ni oGaiptsodnrn.o +5
neonem  Oh .h.ud. atth ekmsa mhuc oerm sen.se aksT!nh ..Ps I hthtuog ohpmneceil was omer of a tyefirtli drug rof wnemo, nisec it lcokbs tvgneaie deebafkc of otgsrene on eth ptatia/hylpthamuirs.oyu uBt in enm het mestys is dneru acfkebde ued ot tenert,otesso nto otres.gen +6
utap2001  lmi enhocep is rsgneteo na,eaoulg ciovmetptie gaotsatin,n not feivctfee ni mn.a 2. heT semmincha fo ohnieeplcm is fekcabed acrnesei fo RH;-ng&tG aicsneer H,H,LSF otn feeecitfv ni yupratiit oeamrlv ptit.ane +1

Obviously the FSH -> spermatogenesis answer is the main idea, but I also think giving exogenous testosterone might actually impair levels of Testosterone in the testes as the concentration needs to be much higher in the testes for functionality due to a binding protein that is produced under stimulation by LH (which would be under neg feedback from exogenous testosterone)

+2/- cmun777(37)

I agree with below, sertoli cells release a testosterone binding protein in response to FSH in order to radically increase testosterone levels within the seminiferous tubules. That is why individuals who take exogenous testosterone have decreased fertility even while taking T.

+2/- lowyield(43)

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 +3  upvote downvote
submitted by โˆ—asharm10(37)
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os his pyrtutia emaadon asw ev,edmro os plroyl sapdrgontoho rwee edevrmo thwi ,it os fi you igve hnrg it to'nw do ythninag as it ;catn dperocu HF/HLS os you evig /shlhf cdyteril ot ciedn gsomiaseetepnsr and ostet syites.snh

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faus305  Yaeh sthi asmke a lot fo ics.ne eTh rnoareti uirityatp upcserod TFLP-AiG FS,H( ,LH HCA,T H,TS rtolnai,cP adn towhrG orm)oeH.n yrPitiuta anadosem rae tsom lcmonmoy itmcrnsoloapa in hte rnoaietr itprut.ayi eH is tsju onw gnnioict the ffceste fo not hgavin HL nad ,HSF fit.irytleni So we nede to leearpc th,seo kaa vige onronstp.gadio +


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