NBME 22 Carboxylation of precursor proteins (NBME Answers)

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Retired NBME 22 Answers

nbme22/Block 3/Question#12 (reveal difficulty score)
An 82-year-old woman has been bedridden since ...
Carboxylation of precursor proteins 🔍 / 📺 / 🌳 / 📖
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+6 upvote downvote
submitted by ∗humble_station(85)

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Warnafir biiihsnt tiV K peddennte sythsseni fo aoctsrf m;a&p tieorsnp.

iVt K si renesaycs rof teh mtiuanaotr of lgonctit orftcas I,I II,V ,IX X and ptneori C pam&; S

oS a rgdu ttha nca tbnihii het xalbitooanycr fo rsuerocrp inotrpse or in rtheo wsdor hibinit hte iauratomnt of hte ctliogtn cfsoatr lwli ersdacee hte iksr of oobrhisstm ni sith .anietpt

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Extra note: Thrombomodulin alpha (a recombinant drug) can increase thrombin degradation and Protein C activation, hence can also be used for anticoagulation. (But this question asked about decrease in which of the following)

+3/- apurva(101)

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submitted by ∗haliburton(224)

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nrairafw shitinbi eth iseyhsnst fo oastrfc I,I IIV, X,I ,X ,C nda S yb boignckl onutredci of ioedidxz mtiavin K. heT eynmez pEoeixd acuReetsd is tiibdihen yb fnrairaw. eTh curddee teicv(a) mfro of i.vt K si a tcoforac fro myt-gauamgalml e.racsyobalx

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link981 oS tsrcfao ,II ,IVI IX, adn X aer ropcruesr sir?opnte FOTG +2

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+0 upvote downvote
submitted by ∗humble_station(85)

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rnifarWa iitsbihn tiV K edndteenp yshnisset of casofrt ;m&pa ip.nretso

Vit K is ynrcseeas orf hte ataormniut fo tctonlig sftocar I,I ,IVI IX, X dna tpoirne C & S

So a dgru atth nca hiiintb hte oltxayrboainc of spuerorrc psretion ro ni eorht wdsor hiinbit hte oirtuaatnm fo eht nocttgil trsocfa lwli aesederc eht rkis fo sbshormoit in iths t.eptnia

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ajss tshi si hwy awrirfan is neivg sa lxyirsahppo rftae itsh eypt of erigssreu +

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-2 upvote downvote
submitted by ∗sup(31)

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Why ton GIP2 yb awy of A?AS lEpslaieyc eignv treoh erwasn oicsche of isntoper C + :S dnt'seo airnwrfa sloa upsrspse ?seeth

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imnotarobotbut riePton C adn S are -hooAcbImtT,tNri os hlhgtoau Winarfar seod edcseera ,tmhe htey wtouln'd scraeede eht t'tasenip kris orf stiorsmboh +1

epr94 the qnuitose ksa esurpp"sniso" of hcwhi one lwil rseeeacd ksri fo osbomirsht fi uyo rsesupsp C and S ihwhc dan th-iocaotinbrmt ouy teg mboicttohr +3

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