NBME 22 Carboxylation of precursor proteins (NBME Answers)

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Retired NBME 22 Answers

nbme22/Block 3/Question#12 (reveal difficulty score)
An 82-year-old woman has been bedridden since ...
Carboxylation of precursor proteins 🔍 / 📺 / 🌳 / 📖
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+6 upvote downvote
submitted by ∗humble_station(85)

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iWrnraaf bistnihi iVt K eptneednd issyeshtn of ftcsrao &a;mp tpon.irse

tiV K si cresysaen rof the otanitramu fo otcgnitl trcosfa II, IVI, X,I X adn petrino C ±a S

oS a urdg hatt nca nibiith eth licoxyatarnbo of srprruceo eorpstni ro in hreto rwods iihnibt the aiuatnmrot fo eth gltction cosrtfa will dasceree the ksir of otbshmoirs in htsi ntpteai.

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Extra note: Thrombomodulin alpha (a recombinant drug) can increase thrombin degradation and Protein C activation, hence can also be used for anticoagulation. (But this question asked about decrease in which of the following)

+3/- apurva(101)

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+2 upvote downvote
submitted by ∗haliburton(224)

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aarrniwf sihtbini eht itensssyh of orfsatc II, ,VII ,IX X, C, nda S yb ibgcnlko cenudirto fo iedxoidz naiivtm K. hTe emenyz xEeoidp euacedsRt is idtnhiebi by waiarfrn. hTe erdcude ca(vtie) from fo .vit K si a ratfcoco fro tga-mlygamauml syaxc.oberla

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link981 oS aroctsf II, VI,I I,X nad X era rusroperc stnoipe?r FOTG +2

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+0 upvote downvote
submitted by ∗humble_station(85)

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ifWrrnaa bhitinsi tVi K nntpedede eshsnstiy fo ocasrtf a&;pm ipsre.otn

Vti K is nsreceyas rof hte amatuntroi fo litgocnt rfostca II, ,IIV IX, X nad etinrpo C a&;pm S

So a rgud htat can hinitib eht loraobntyicax of porcerrus osirnpte or ni ohert sdrow ibtnihi hte anatuitrmo of het iclontgt tfcrsao lwil eecresad het sikr of ostoihmbrs ni tshi .aitpnte

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ajss hsit is why fairrwna is iegvn as syxioprhpal terfa htis ytep of ssergieru +

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-2 upvote downvote
submitted by ∗sup(31)

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yWh tno 2GIP by ywa of SA?A eElclypisa eginv reoht seranw osihcec of srtonpie C + S: otsn'de rwfanira soal pspuress ehset?

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imnotarobotbut eiPrnto C nda S rea ,-tcArhbotioINTm os utohhgla iaWafrnr dsoe edaeesrc ,meht tyeh lou'tdwn edaecesr teh ap'itstne irks orf miotbrshos +1

epr94 teh qoeiunts ask us"sneporis"p fo ihchw eon ilwl eradscee iksr of ssbotriomh fi ouy sssupper C adn S hhicw dna onctihorttabi-m yuo egt tbrcmhoiot +3

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