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Retired NBME 21 Answers

nbme21/Block 1/Question#12 (reveal difficulty score)
A 25-year-old nulligravid woman comes to the ...
Endometrial hyperplasia ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—mcl(671)
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COSP si aeossiatdc with rnbalmoa itucnropod of esx ,tesidsor ligncndiu dnnositcyfu of gnteseor cutonpodir nad eperntg.seroo nclhaoiCylr evleetda vlesle of ngoseret nca cseau artmidneelo saepiyar.hpl

5e.c/wP/cmh/sino1aM9npv:rgsct/mbn7t9wt..iw9/Ci3/.phll

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meningitis  yhW tnsi it sorie?ndstieom doClu eoemsno pleh em tou on sih?t +2
meningitis  roS,yr I asw nonscfiug thiw rhheig rksi rfo aeedimnrotl aiomarcnc. +1
vi_capsule  nsteorEg is esbensrloip orf lcyicacl bdeglnei and inap scaasdtioe twhi tesndioorimes nchee sptnioreg si a atetnretm oitdayl.m Btu egetnrso sint a iskr cartof rfo oreiEiss.tmdno tareRh resteh rdrtoaereg o,fwl laapticemt nimtasnrtfooar tec hteoires rae oelbsnpesri fro dtnosore.imsie +1
sympathetikey  fTw yuo egt os hnortw off yb a tceirpu htta uyo dtno' erad teh oistuqne .ryperlpo +34
hyperfukus  iingnms@iet ikd if u lstli caer llo but awsyla og kbac to eocmdnciseetp=ooirsit eleanidmotr tussei soutied of eht restuu so you anc elru ti tuo necsi dscieanre sgerteno dwulo caues you ot hvae ernswoed nsdotrimeeios or a rtihcek oen but not .etcl.yy.ourid nca ees teh pusmcl fo the oceisllfl in eht eroasiv if yuo olko pesur esolc os atth glano htwi eth npnerettaios astke uoy to POCS dna anmytei oyu od'nt ahev a ybab or yast in eth rlieroiaevftp treogn(peasseh )hapse oyu etg omtrlneaide sp&hai;t-yglale-ptp&yailmn-i-trgrto;oetea-lifru rcnmoaaic +2
lovebug  FA ,9120 paeg 613 +1
lovebug  Ohrte snrawe )igsMeH oednryms : dt ira of 1) ioavrna oir,afbm 2) tasscie, 3) llarupe fin.esfuo iโ€œPngโ€ull aesnisotn in gnoir. AF 1209, pg 263 +1
xw1984  st'In nopoit G, aoLemaoymti tir,ue asadticeso whit ihgh gesonrte ?vllee Pre FA 00,22 ibfdrio si setonrge iitsee.snv +2
ownersucks  wx189@4 rsosg igmea lwodu owsh petiullm orwhlde aesmss +1

I feel the clearest way to understand this question/answer hasn't been stated yet. Recall that the cysts in PCOS are unruptured follicles. If follicles don't rupture, you won't have corpus lutea, which won't secrete progesterone and therefore menstruation won't occur. This leads to unopposed estrogen and disruption of the menstrual cycle, which can cause endometrial hyperplasia.

+20/- pg32(218)

The patient here is obese and has hirsutism. Her androgens are converted to estrogens in peripheral fat, causing hyperestrogenism.

The exact reason for increased androgens in PCOS is unclear, but it involves an increased LH:FSH ratio. Relative decrease in FSH inhibits estradiol synthesis in granulose cells and favors androgen production in theca cells.



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submitted by โˆ—pparalpha(93)
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atposlimcinoC of C:SOP

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nlrodEmeati recanceirlps=yapah

aesrencdI mgcraiiears trae

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