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Retired NBME 21 Answers

nbme21/Block 1/Question#12 (reveal difficulty score)
A 25-year-old nulligravid woman comes to the ...
Endometrial hyperplasia ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—mcl(671)
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CSPO si tsdceaiaos wthi manoblar octduioprn fo esx rst,esoid niulidcng tofnusindcy of ongester uotncrpido and tgnso.orpreee coyialChrln valetdee lsevle fo rnotesge acn saecu irndoteamle epilhpy.saar

//bh7nvo//9giC1etsprmwmsi:itlhn.cwatlP.c.95/.3c/Mw9np

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meningitis  Why istn it erd?iisotmeson oCdlu omosnee ephl em out on sith? +2
meningitis  yo,rSr I asw ufocgsinn whit igrheh isrk rfo eioaltdnmer acmnicroa. +1
vi_capsule  Eegntros si epbsolenrsi fro claciycl bileegdn and ainp sdtcioesaa wiht etimroidonses echne isotrgnep is a amttentre dlamoity. But engosret sitn a iskr trfcao ofr tdr.oenoEssmii Rerath hsetre taedregrro wlf,o lcitpatame oirtnaosmtfanr ect sroheite rea beienspslor fro rstnoesmdo.eii +1
sympathetikey  wTf you gte so orthwn off yb a tcpreiu htta uyo ot'nd adre het nqtiseou poeyrpl.r +34
hyperfukus  emg@itinsni idk if u lslit cear llo utb slwaya go bcka ot ssmitied=nitooceoercp iloemetdrna essuit estudoi fo eht rtuues os oyu nac rlue ti tou nesic aenedcirs ereostng wudlo ueasc oyu ot have eodwrsen domestiosrien ro a kitrech noe but tno yiluto..ecyrd. acn see eht cpuslm fo het oilclflse ni eht arevsio if uyo loko ureps sceol so ttha lnoag itwh het rttniosnaeep kesta you to POSC nad maeinty yuo 'otdn ehav a abyb or ayts in eht vilrpefrieato sngaes(erhopte phse)a you tge lieeormatdn t&-the-pre-ltmifapup&y;stl;lyeogaanraoil-tgir-i acoiarmnc +2
lovebug  FA 0291, paeg 316 +1
lovebug  Oetrh nsrwae igeMs)H mnyroeds : tr adi of 1) invarao fbmrioa, 2) ectisa,s )3 ularpel sfifeuo.n โ€luiโ€œngPl sntseiaon ni .oingr AF 92,10 pg 623 +1
xw1984  'tsIn tionpo G, maytaieLoom truie, dsoietcasa twih hgih rnosegte el?lev reP AF 00,22 ofidbri is rtngsoee estsevni.i +2
ownersucks  418xw@9 grsos emaig wuold whos liplemtu dloehwr semass +1

I feel the clearest way to understand this question/answer hasn't been stated yet. Recall that the cysts in PCOS are unruptured follicles. If follicles don't rupture, you won't have corpus lutea, which won't secrete progesterone and therefore menstruation won't occur. This leads to unopposed estrogen and disruption of the menstrual cycle, which can cause endometrial hyperplasia.

+20/- pg32(218)

The patient here is obese and has hirsutism. Her androgens are converted to estrogens in peripheral fat, causing hyperestrogenism.

The exact reason for increased androgens in PCOS is unclear, but it involves an increased LH:FSH ratio. Relative decrease in FSH inhibits estradiol synthesis in granulose cells and favors androgen production in theca cells.



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submitted by โˆ—pparalpha(93)
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minscalipCtoo fo :OSPC

ralaCiudosvcra neevts

pyeT 2 ebdaetsi ltmuilse

dlEroimetna crnaeclaayei=rpshp

craIndsee mgicaerasir rate

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