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Retired NBME 21 Answers

nbme21/Block 1/Question#12 (reveal difficulty score)
A 25-year-old nulligravid woman comes to the ...
Endometrial hyperplasia ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—mcl(671)
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OSPC si iaestdasco with aonmrbla ptinurdcoo fo exs s,sorietd nuiilndcg dtiosunycfn fo retnoegs pritcodoun nad .sortenogerpe nroiycalClh vtaleeed veslle fo nerstoge anc cuase teloandirem eslia.yarpph

n/cn.wtml9/rcpewm./M./l91itg.t/avw3ns/hi7pC9bhcisPo:5

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meningitis  hWy sitn ti mdoiseseri?nto oluCd ooesmne lpeh me tou on ?iths +2
meningitis  rS,roy I swa uisgfncon tiwh ghrieh skir ofr aeimdlonter ona.icacmr +1
vi_capsule  sEerntog is ipeossbnerl rof ilcycacl indglbee dna apin aocsatside hitw tmrensdeooiis ehnec gopestinr si a etttranem .oyailmdt Btu etnsgore stni a srik ctoafr orf tiEsie.rdonsom Rthrea tehser erdrtgeroa owlf, tcpaeilatm arnofmraotisnt cte oihtrees rea sblneorepsi orf omsndteioes.ir +1
sympathetikey  wTf ouy etg so wntrho ffo by a trucipe that uyo n'tod dera het oiuetqsn ep.porryl +34
hyperfukus  tm@sniigine kid if u lstli erac llo but aayswl go cbka to ioecoemios=trecnipdts ednmiltreoa esusti iestodu fo eth seturu so uyo acn lreu it tuo ceisn sacrndeei etsoegrn ulowd csuea oyu ot aehv eeswrdon donsiemetoris ro a chirekt eon but not iuy.tld.cory.e nca see eth ulmcsp fo eht lieclsflo in het aviseor fi you olok rpues olcse so hatt algno ihwt eht oespnrtetani atkes uoy ot CPSO and tniyema yuo todn' ahve a ybba ro yast in the ftparoievirel (enprhsaoteseg )saehp yuo teg elindtraeom aag-thptm-y&orluopplntlefegrsr;;-y-iia&a-iieltt nocmracia +2
lovebug  FA 9201, geap 361 +1
lovebug  rehtO wsarne )seHMgi nmoresdy : taird of 1) iornaav fobmira, )2 aicste,s )3 lrlpeua isu.enffo ngliโ€uโ€œPl noieastns ni .ngiro AF 2,910 gp 632 +1
xw1984  'tIsn ptooni ,G oammotyaiLe tru,ei aeotascdis htwi gihh ensotreg vell?e rPe FA 2,002 bofidri is eretongs eetvsni.si +2
ownersucks  x8149w@ grsos amegi woldu oshw eiulmltp rwdheol sesmsa +1

I feel the clearest way to understand this question/answer hasn't been stated yet. Recall that the cysts in PCOS are unruptured follicles. If follicles don't rupture, you won't have corpus lutea, which won't secrete progesterone and therefore menstruation won't occur. This leads to unopposed estrogen and disruption of the menstrual cycle, which can cause endometrial hyperplasia.

+20/- pg32(218)

The patient here is obese and has hirsutism. Her androgens are converted to estrogens in peripheral fat, causing hyperestrogenism.

The exact reason for increased androgens in PCOS is unclear, but it involves an increased LH:FSH ratio. Relative decrease in FSH inhibits estradiol synthesis in granulose cells and favors androgen production in theca cells.


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submitted by โˆ—pparalpha(93)
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mnaioctoplCsi of CP:OS

iCaraldvcousar nveest

Tyep 2 deebtais tsumleli

oldierntaEm ancecrhilpa=prasye

nerecsIda riasemgiarc raet

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