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Retired NBME 21 Answers

nbme21/Block 1/Question#12 (reveal difficulty score)
A 25-year-old nulligravid woman comes to the ...
Endometrial hyperplasia ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—mcl(671)
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CSPO is dcsstiaaeo twhi oaralbnm ucdpotnoir of esx sodets,ri idgninulc osuncitfdny of snrtegeo tpiorcdnou nda ne.prroegeost ralyolcihCn aedletev lvesle of getsrnoe cna saceu eamtnrdoile yp.hrasielap

nCilp:cttp.s7c3nMw/a/h9hcnm//v.me.r5s/b.woPi/9gtiw19l

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meningitis  yWh sint it seiirmd?eonost oCudl eosemon help me tuo no his?t +2
meningitis  y,rSor I wsa snoginfuc iwth igehrh rsik rof nmoerltadei m.ncarocia +1
vi_capsule  tnoersEg si eneorlibssp rof lccliacy iegebndl adn iapn castaosedi htwi doitnsmeersoi ecnhe rtpsienog is a tratentem idot.lamy tuB tsrneeog itns a ksir faotrc orf n.tsrEideomois rRathe hestre rgaorerdet lw,fo amtplticea faoramntinosrt ect hoesteri rea boelepsrsin rof rss.diitoneoem +1
sympathetikey  wTf yuo get so whrtno ffo by a eruipct atth oyu td'no arde eth suitnoqe lrpopre.y +34
hyperfukus  neg@itimnsi kid if u ltlsi eacr llo utb aslawy go bkca ot tds=meinoortioieccpse mtoirneleda tsiuse uitodes fo the rusetu so ouy nca elur ti out icnes enrdsaiec sntreeog doluw cseau oyu ot ahev eodnwsre sosroendiitme ro a hkcreti oen ubt tno uri.y.yt.ocdel acn ees het msulcp fo eth icefllsol ni eht osrieva if ouy oklo eupsr sleoc so ahtt aolng whti het renetnaopits sekat you to OCPS adn enitmya oyu no'dt aehv a byab or tasy in eth evrtaioiferpl st(paeherosgne aeh)ps uyo gte oilradtmnee opnet-m&iyyeoa;-eptla-ilt;tirirhla-stulp-fgg&ar romcniaca +2
lovebug  AF 901,2 gpea 361 +1
lovebug  rOthe nraesw eiHM)sg smyroedn : r idta fo )1 naovria i,farobm )2 ,icsaset 3) aupelrl ofnufsi.e ngiโ€œlPuโ€l nnsieatos in .rgnio FA 201,9 gp 326 +1
xw1984  sn'tI iootnp ,G imoaLtayome tieu,r acdsoteais with ghih regtnsoe ?velle rPe FA 220,0 irbfdoi si gotsneer iseitn.vse +2
ownersucks  @189x4w gross eiagm wlduo hwos eilputml elrdhwo sassem +1

I feel the clearest way to understand this question/answer hasn't been stated yet. Recall that the cysts in PCOS are unruptured follicles. If follicles don't rupture, you won't have corpus lutea, which won't secrete progesterone and therefore menstruation won't occur. This leads to unopposed estrogen and disruption of the menstrual cycle, which can cause endometrial hyperplasia.

+20/- pg32(218)

The patient here is obese and has hirsutism. Her androgens are converted to estrogens in peripheral fat, causing hyperestrogenism.

The exact reason for increased androgens in PCOS is unclear, but it involves an increased LH:FSH ratio. Relative decrease in FSH inhibits estradiol synthesis in granulose cells and favors androgen production in theca cells.


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submitted by โˆ—pparalpha(93)
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noltiscioapmC of SP:OC

orsviarulCdaca tsvnee

Tpey 2 tdeiesba ultlmsie

oldErntmeia rcanceyalaeri=ppsh

sIrancdee risiamcgare rtea

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