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Retired NBME 21 Answers

nbme21/Block 1/Question#12 (reveal difficulty score)
A 25-year-old nulligravid woman comes to the ...
Endometrial hyperplasia ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—mcl(671)
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COSP si adssacitoe htwi abromlna dptinrocou of sex drsoei,st gliunnidc iynsndtfocu of gsetnore driotpncuo dna .pereetsnoogr lCnyahloric lvtadeee leelvs fo tgensore anc useac antleoimred paarp.eilysh

p9.rivcill79MCn/gnews///b:/5t3o9wh.nci.waht1mP/cmpst.

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meningitis  hyW ntsi ti ti?mnoisdseoer uCdol eomsnoe pehl em tuo on iths? +2
meningitis  S,oryr I wsa ocngfsinu whit heghir kisr orf riedmonealt oinmcaarc. +1
vi_capsule  tneoEsrg is pbnisesoler orf iaclcycl dbeegiln nad ipan staisaoecd ihwt smrsneiieootd hence srpentgio is a taemetrtn alyiot.md uBt nosrgeet nits a rski ftrcao rof .sidtenoEsmior Rrtahe eesrht rgartordee ,wlfo etlctaimpa nsaoraminrtoft etc sroehtei ear boelsiespnr rof smdotis.nioere +1
sympathetikey  Tfw oyu tge os ntwrho fof by a ertiucp atht ouy 'ndot erda het qoiuntes ryeplpro. +34
hyperfukus  gsenit@niim dik fi u siltl care oll ubt slawya og bcak ot piosermiisctne=tcodoe ntdelmieora utiess oitdsue fo the uetrus os yuo can uelr it tou nesci csdeierna toensegr olwdu uaecs ouy ot veha doreeswn eimoodisrtesn or a hrkiect oen tub ont .oylui.ytdcre. acn ees eht pclusm of eth oclleifsl in het eorvisa if you loko respu loesc so thta lagon wthi eht iroenptsetan teksa yuo to CPSO dan nyemtia ouy tndo' veha a byba ro tsay in eht rrlaiviopefet eosgertpan(she sahp)e uoy tge iermteonald yhl;amgtr-er-&pel;ulgtastaproin--e&iopaf-ltiyti orcamanic +2
lovebug  FA 0291, gpae 613 +1
lovebug  hOetr erawns eigH)Ms moyredsn : ria dt of )1 niravao ,ofmirab 2) itsesa,c )3 ueparll fu.oisfne llโ€โ€œnugiP neaitonss in onigr. AF 10,29 pg 632 +1
xw1984  sIt'n ooiptn G, mioaLyomeat ,iurte taidsacsoe wthi gihh torenegs l?veel erP AF ,2200 fibdior si gnretose tsnvi.siee +2
ownersucks  @419w8x orssg mgiea oluwd hsow lmtiulpe ohrlwed emsssa +1

I feel the clearest way to understand this question/answer hasn't been stated yet. Recall that the cysts in PCOS are unruptured follicles. If follicles don't rupture, you won't have corpus lutea, which won't secrete progesterone and therefore menstruation won't occur. This leads to unopposed estrogen and disruption of the menstrual cycle, which can cause endometrial hyperplasia.

+20/- pg32(218)

The patient here is obese and has hirsutism. Her androgens are converted to estrogens in peripheral fat, causing hyperestrogenism.

The exact reason for increased androgens in PCOS is unclear, but it involves an increased LH:FSH ratio. Relative decrease in FSH inhibits estradiol synthesis in granulose cells and favors androgen production in theca cells.


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submitted by โˆ—pparalpha(93)
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ponmoctCliias of O:PSC

acaasidulrvroC esvent

yTpe 2 tabdeeis sllmeitu

lomrnedEtia accrnepilasyhpr=ea

deIrsneca igramseirca aetr

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