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Retired NBME 21 Answers

nbme21/Block 1/Question#12 (reveal difficulty score)
A 25-year-old nulligravid woman comes to the ...
Endometrial hyperplasia ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—mcl(671)
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SCOP si tdsaiesoca whit lmaornba rictdounpo of esx ,trisesod glduniicn nfnyicodtsu fo sroetnge tpinrcoduo dan tereo.spnroge ahcClrloiyn levedeta lslvee of ntreoegs cna escau nrdeaietmol lpayesa.hrpi

b1ch/rs/lP5ilpCn/9nno.wiwm3p/c/ht.7gt:Mtmwsva/.i.ec99

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meningitis  Wyh isnt it ?seinredtooism oduCl seemono ehpl me uot no s?ith +2
meningitis  Syrr,o I asw sfnoucgin iwht ihhegr sikr rfo moneiltdare .oniarcmac +1
vi_capsule  Eotgsern si lsrsoebnpie rof yalicclc leiegnbd nda pani adessoitca with otsimoensdeir eehnc eorigstpn is a tteeartnm lma.otdyi tuB grnoeets stin a srik fatcro rfo dmreEoitns.iso raheRt heters retoagredr w,flo caelpamitt nsimtfaotaronr ect ehsreiot are renpisloseb for eeosri.tsnodim +1
sympathetikey  wfT yuo teg so tnohrw off yb a tripceu that ouy dnt'o erda teh ieosnqtu ypplorr.e +34
hyperfukus  mgteisii@nn idk if u tslli arce llo btu saywal go kabc ot eocionmtesdiitsor=ecp traemdinole siseut udsioet fo hte rustue so uoy acn uelr it tou nesic iaecendsr nsgtreoe ouwdl acsue uyo to ahve donrewse omistonsrdeei ro a ckhiter eon utb otn udor.yti.clye. can see the upcmsl fo the eillsfcol ni eht vieraso if ouy loko uspre csleo os htta glaon whti hte atnpoteisren kstae oyu ot SPCO nad eamnity uoy 'ntod aevh a ybba ro tyas in eht prorileevafit snreo(epastegh hep)as you etg mrloaidenet tii&luyllm-a-e;prtrptorl-aoet;ag-nts&eiiyafg-hp rnocmiaac +2
lovebug  FA 90,12 paeg 316 +1
lovebug  Orteh rnwase ei)sgHM enmdyors : tadri of )1 aanvior f,rimoba )2 ,saectis )3 upelarl .suoffeni nuilโ€lgPโ€œ snsenotia ni gonir. AF 1,290 pg 263 +1
xw1984  Is'nt ointop ,G aaLoyoimemt r,etui tdssaaieco thiw high srtonege lelve? Pre FA 02,02 rfdiiob is resgtone iiesest.nv +2
ownersucks  w814x9@ rossg eigam doulw show pmlilteu lwoerdh msasse +1

I feel the clearest way to understand this question/answer hasn't been stated yet. Recall that the cysts in PCOS are unruptured follicles. If follicles don't rupture, you won't have corpus lutea, which won't secrete progesterone and therefore menstruation won't occur. This leads to unopposed estrogen and disruption of the menstrual cycle, which can cause endometrial hyperplasia.

+20/- pg32(218)

The patient here is obese and has hirsutism. Her androgens are converted to estrogens in peripheral fat, causing hyperestrogenism.

The exact reason for increased androgens in PCOS is unclear, but it involves an increased LH:FSH ratio. Relative decrease in FSH inhibits estradiol synthesis in granulose cells and favors androgen production in theca cells.


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submitted by โˆ—pparalpha(93)
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apnmstciiolCo fo OC:PS

iaasoCdrualcvr seenvt

epTy 2 adietseb melisltu

aEmedtnorli cnaecrih=sarppayle

srcdnIaee rcamsigaire reat

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