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Retired NBME 21 Answers

nbme21/Block 1/Question#12 (reveal difficulty score)
A 25-year-old nulligravid woman comes to the ...
Endometrial hyperplasia ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—mcl(671)
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SCPO si teoaacsdsi twih nlbaamor pinrdoutoc of exs sedoi,trs glicnnuid ydtoucfisnn of etosnrge tcundpiroo nad orgt.sereonep Cclolyairnh edeleavt eslvle of gnsoeter can aecus taioenderml yrap.liphaes

5cmw9i..1p9mne/pbPr7anClthtwol/9/sMw3//.vthnigci.sc/:

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meningitis  yWh tsin ti etoimnseido?rs Cloud enoemos hepl em otu on s?thi +2
meningitis  rS,ryo I wsa icfgnsuon ihwt eihghr iksr rof tmerdneoila iomrcacan. +1
vi_capsule  osErnteg si renebpsilso for icylaccl eglinedb dna naip tcaaiossed with eodismitsrone ceneh niestrgop is a ttrtmanee .doymiatl tuB trnoeesg nsit a riks tarcof rfo enEodsmris.oit aRrteh esrhet atdrrreoge ,owfl ctailematp anrfottarinoms cte hieersot rea erbopilnses for smriosdietneo. +1
sympathetikey  Tfw uoy teg so rnwoth ffo yb a cetriup atht yuo n'tdo ared hte uqiotens lrperoy.p +34
hyperfukus  innsmi@tegi ikd fi u sllti care oll btu lysaaw og abkc to ecioidtestprnocmis=eo tomaeldnier suseit iueotds fo teh utuers os you can leru it otu sncie dsriancee trenegos wdlou cesau uyo ot ehav eowdrnes ndrioeismtsoe ro a rtechki eno btu ont yyodl.e.t.uirc acn ees hte msupcl fo hte selocflli ni eth esrovia if you olok perus csleo so htat olgan thiw teh erenpotiasnt astke uyo to PSCO adn eitynma you do'nt hvae a bbay or tysa ni eht reflpoterivia oareetnpshsge( asep)h you etg rltineadeom lli-igatsrirety-at-nayep;lt-rhaep;o&fumg&oi-ptl cirncmaoa +2
lovebug  AF 2,109 eapg 163 +1
lovebug  hterO saernw MeigH)s nodsmrey : d airt of )1 avarion bmfa,rio )2 s,icatse )3 ellrpua snofue.fi liโ€œuโ€lgPn snoseinta in or.ngi FA 1,920 pg 236 +1
xw1984  nt'Is pontoi G, otaioLmeyma tuer,i ctssadoeia twih hhig oeegstrn ?eevll Per AF 0022, drioibf si gntseroe eesni.tvis +2
ownersucks  8@w914x gossr egiam owdlu hsow mtlelpiu rwhelod smseas +1

I feel the clearest way to understand this question/answer hasn't been stated yet. Recall that the cysts in PCOS are unruptured follicles. If follicles don't rupture, you won't have corpus lutea, which won't secrete progesterone and therefore menstruation won't occur. This leads to unopposed estrogen and disruption of the menstrual cycle, which can cause endometrial hyperplasia.

+20/- pg32(218)

The patient here is obese and has hirsutism. Her androgens are converted to estrogens in peripheral fat, causing hyperestrogenism.

The exact reason for increased androgens in PCOS is unclear, but it involves an increased LH:FSH ratio. Relative decrease in FSH inhibits estradiol synthesis in granulose cells and favors androgen production in theca cells.


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submitted by โˆ—pparalpha(93)
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nimsatpcoCloi of PSO:C

rlcuodaCaarsiv nsetve

Tyep 2 ateeibsd ltlmueis

erodnamiltE aeccnrpl=hpiresyaa

ecadsreIn iraesaigrmc taer

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