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Retired NBME 22 Answers

nbme22/Block 1/Question#35 (reveal difficulty score)
A 35-year-old man is brought to the hospital ...
Alteration of the thermostatic set point ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +20  upvote downvote
submitted by โˆ—keycompany(351)
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rtietaloAn of teh tcmsthetaori ets tpnoi is a amiahohlpcyt eospcsr mdeiteda yb tlsidsnnrapago nda is dnepndieetn of hte shtpteaciym nsvorue ysmtes.

B, C, ,D adn E all qrereui ytaispcemth snevre to tlcelii a esspne.ro

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pg32  naC aoenyn panixle eht cmsimnhae dihnbe nrihvgsei and teh tcpiamhetsy ueosvnr ems?tys +4
mdmikek89  tsahHyumloap yerlas ruhoght hte oconumait vunrsoe msse.ty uYo utc eth leary, oyu nac olny cheang the ermoscittath ets n,topi utb the oybd t'nca .etrca +1
umpalumpa  yuGs, I hnikt htat rfo het vhigsneir tlvatnierea hte point si TNO atth pttsecaimyh vrenes rtnlcoo rseghivni ,cultyala( I ha'envt fdonu iactslre no bmpeud hatt sasy atth nehivisgr si cntoeordll yb emaitt.hpy)sc HeT taeessi ayw ot nhtik si ttha sith tp ash a ycitesms eontiifcn a(ak mtIissS-eRycS ralfmatminyo ssrepnoe yn)m.rsode In SRS,I tp nac ehva l&;T53t C ro 8;g3t& C, BUT it is rmoe momcno ot avhe reevf ahnt .mayopihhtre roCgednisni th,si yuo nca yilase rlteu-ou the vsgirnhie na.atevitler +1

Even brown fat needs SNS == release of NE == binds to beta 3 receptor on fat == uncoupling of ox phos!

+6/- apurva(101)


 +4  upvote downvote
submitted by โˆ—qfever(67)
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pauylstahoHm ocltinlngro tetaeerupmr set intpo si belyfri tnndmoeei in taamPoh 8120 teiiodn peag ,31 perhaCt 2 III arandilC nsigs fo otmaimfinnal .D eevrF

yosePegn -;t&g amrchgopae rlseeae -I1L and NFT gt-&; deneaisrc yyxslogecnaeco itayticv ni ymtopahaslhu acpvuirrslae elslc tg;&- ndacesrie huoastlhapym EGP2 ;gt-& dasire erpmtauerte est pntio

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 +0  upvote downvote
submitted by gribear(0)
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aCn eoeosmn iexplan hyw wnhe uoy aentctsr eth lspnia ocdr oeiupsrr to hte eellv fo ypmsahttcie oltofwu -- dna uyo etg a escsyitm nintoefic -- eht orsepnse si lratonteia fo teh tetcatirhsom tes oitn?p

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its_raining_jimbos  So I sheoc thta noe ausebce ets ipnot si tecrlodlno by the ulhoyatmpahs 2E(PG nad LI-1 deaiemt efevr in het hoytmusapalh) dan teh etsr of eth rewnsa esiocch veivnold oeigmnsth olweb eht evlel htta has bene .srecttaedn oNt 1%00 resu if sahโ€™tt cataucre uohgth. +5
noselex  reegdA thwi @biiinas_mo_tjsirgn -- vreFe si atdeedmi yb ritlaneg est ipont in ptmshahou.aly All teh rheto e,sochci sa rfa sa I can tlel, nevvoil mateihysptc neevsr dna htrie eceffst ta etgrat oagrsn. +2

You might not be able to change the temperature because you have no sympathetic outflow, but the actual "resetting" of the thermostatic set point is mediated via the hypothalamus and prostaglandins

+2/- spow(50)


 -1  upvote downvote
submitted by โˆ—j000(17)
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i got iths tensqiuo wn,gro tub i ktnih hatw iths usqnetoi si layler gnakis si hwat shpeapn in a ssctyime cii:tnfoen hcwih is fveer

ni cimestys itfcni,eon eht sotm soouvbi snig ot kloo orf si a efrev, nto neyscraelis s,vregnhii ges,niwat etah rpoctunido yb rbnwo tf,a ect.

nda owh osed vrfee ?cruoc ilke emnooes yaaldre dn:eniotem seypgeon ->-; pgerhacsaom aelrnisge 1IL dan FTN hhicw sscirnaee CXO iiattvyc ni hothpauslmay eaiurrlvcsap scle,l eiacesnr piductnoor fo EG2P in umhlsapyotha dan etsre the amerurptete set tpion.

i knhti hte elhwo aesprh emlcpot"e tcirnoestan of het isanlp codr isopruer to hte elelv fo cttei..."yhspma is a noiiscartdt. ti sujt slelt uoy htat opmnleedvet of a efver ahs tnohgni to od wthi it

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j000  pleemdotevn of a eefrv in sytmscie oiecfntin sha tnngoih to do wthi chmattsieyp vsrnoue fw,ol so evne is't reudnij, ferev owuld tills ocr.cu I hitnk isth tnosueiq is utjs insagk woh esdo efrve ocrcu in nofcmieinlmf/iitotaann aotus.iitn +1
b1ackcoffee  ,So owh do oyu lainexp the cultaa freev by utjs giangnch the etos?hr?atmt eerFv ec'ftef' SI ruend eyiatptShmc tnoclor, tjsu hte angcgnhi eht ertmeurptea ekl(i mreh)sottat si itedamde by sioktency dna m.lhayauspoth +2
j000  oh i ese ahwt yuo ,nema ellw i iddt'n wkno ht,at so kntsah for iilcrgyanf ttah. vehoerw, eabsd no oyru iaonlaxe,ntp ti wdluo ltsli get su to eht rghit nwares iwchh si rtelai"oant fo atcresotmhit tse p"toin, ont het efrve ctefef efti.sl +1

So, how do you explain the actual fever by just changing the thermostat?? Fever 'effect' IS under Sympathetic control, just the changing the temperature (like thermostat) is mediated by cytokines and hypothalamus

+1/- b1ackcoffee(115)


 -1  upvote downvote
submitted by โˆ—mdmikek89(6)
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Okya syob nda grils tsih eutqsoin si aseire naht yuo hkt.ni

tyaupmlsHhao saelry aiv eth shpctimeyat nsovure esymts to oltcnro eth dyob wenh a wne ste niopt as bene raeedhc in elst e...cs.vuea.seyraf. b.i.efyco..nint.

fI het cienocnton newteeb eht typhasalumoh nda nslapi dcor m(iaynl eht thmaeipcyts o)lfwtou is cut, the suhaltma coantn eyarl eht bdoy toercain fo a ,eefrv tub hte yaluahstpmho tlifse nca lltis acheng het ste itno.p

oBom

inthiW hte nraib, hte noicmotua vosnreu esytms si ultreedga yb the .tlsuhmayhaop itAomoucn fcsoiunnt icdelnu orcotnl of aitrronis,ep adcrcia iuelrngoat th(e cradcia tlocnro e)cnret, rvotoosma iytitavc (het marovoots te,c)ren dan irnaetc ferxle contasi hcus sa ichug,ong gnesenz,i wnilswgalo and im.itgvno

E-B rcuoc sa a ultser of a hncage in tse nit.op

A apepshn ot ecusa hte EB- wenh a ewn ets oitnp is ce.rhaed

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 -1  upvote downvote
submitted by โˆ—isaacyo94(13)
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In eictmsys cofiitnne, dtwu'nol yuo gte cutauoens IoDvILNAsTOa .(ei. rsieibdvttui sk?och) Thsi swa ym nnogsraie orf cnoigosh B) in stih kcway ietuons.q

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neilfespiritu  eaSm +1



 -3  upvote downvote
submitted by โˆ—gh889(154)
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From kunkoyShedeaorHno no dd:erit

thWa teh stinquoe is itntgge ta si het thcsmeyatpi inhac asw das.epr tI aws a ibterler ayw fo gdoinrw i.t

ruYo trainreo ytaluspoahhm is lneiebprsso rof inlgcoo rtaseefu adn si dnure ythiaaacspetprm r.ctloon A sileon dluwo asuce aihe.hyeprmtr

roYu oiortrspe ythphmsaulao si bnploeesris for niegtha henw r'yuoe cldo nad ot aregtene eht evFre nrpsoees adn is uednr tyscmpeihat ln.otrco A nolise ouldw ceaus amyioth.hpre

In itsh eoustinq it is slmiyp giansk a sronpe sgte cksi, huaapstlmhyo aws pd,ears hwat esapph.n

:Aenrsw myatuhohpals lwil itlls be bael to vtleeea ets ydbo rtaeueptrem to ltatbe cone.niitf

inH:t FI yeth igev a neqistou almiris to ihst but owerdder to edlniuc a seonli fo teh ttmaipycesh resfib or of eht mhpsulaa,yhto yuo udolw ni trun NTO be ebla to gntraeee a efrev oeenrsps to .nifcnieot ehT halohaymputs loudw be relyenit nedur tpraseatpchiaym tloncor

hsiT sadd more ntctoxe ot hte atcf teh Q etsast htat het iaeysmhtctsp wsa esrpad

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oslerweberrendu  S,o itsh assy iteycaspthm olas rpedsa dna otshlyuapmha soal a.edsrp ehTn athw aws orwgn itwh tshi ianclcli eas?c? +1
adong  i hnkit eht tphiemasyct stsmey is ullyatac marpdiie c/b tsi' cut eeofrb it nca .wlo"t."fu.ato steal si't eht olyn way sith seamk essne +4
suckitnbme  I .eager I kinth teh nqteosui mest si giasyn eht yteathismscp wree soin.dlee Not ahtt hyet rwee .spdare +4



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