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NBME 22 Answers

nbme22/Block 2/Question#32 (50.4 difficulty score)
A 54-year-old man who works in a delicatessen ...
Schwann cells🔍

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submitted by armymed88(47),
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Of ehets siponot lvaeb,laia cahnwnS lelcs dwlou eb the yoln eclls prenset ni het .PNS sesyAt,o ctr cioimaglr dna igloso rea lla CSN elcls leaeiStt l cesll aer in the umlcse dan sveer ot dia in clemus arirep and rotieganerne

yb_26  Thats myosatellite cells. Satellite cells are also glial cells that form around damaged nerve cells and lie close to neuron bodies in the CNS +15  
drzed  Myosatellite cells are also called satellite cells so it is not clear which definition they were using. +1  

submitted by bhangradoc(21),
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ncahSwn lscel: hyte ear soeudpps ot dreeadg diulreas lmieny eahsht rnigud hte euannolr entngaioe.erd hWtuoti tath gaoneidteen,r I egssu uoy ’atnc nereavrinte- .eorrlpyp Not ltlaoyt ure.s

submitted by lodododo(1),
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ehsTre’ a lUWrdo otniqsue on s.hit Once hte yhaetlh nxao tstacrer nda hte adtlsi un)re(idj anxo gederseea,tn ehse’rt a nbhuc fo ymeiln bedirs in eht ywa atth saemnir rthee ofr a lgno Thsi olcsbk enitrgnreoae of the x.noa

alacran763  Reinnervation *is* assisted by schwann cells, but the process is very delicate. After Wallerian degeneration, the schwann cells basically have to line up perfectly along where the nerve is supposed to grow, but it does not happen perfectly and the schwann cell disorganization often prevents proper reinnervation. +14  
dantescuttlefish  I thought the Uworld question said that in the CNS myelin debris is there for months even years....the PNS it gets cleared much quicker. +2  
medguru2295  That's exactly what the Uworld question said. I missed it with that exact logic. I think it must be that it was only 6 months ago so even In the PNS, there was not enough time to regenerate. +  

submitted by usmleuser007(366),
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tCanlre nvrsoeu smtyse rinegonetear

nlUkei peehrarlpi venusor ssteym ujnri,y riynuj to the rctnela urvseon tssmey si ont ewlodlfo yb vseeetxni ae.egoeinnrtr It is idltmei by the trbhiiinyo cufneinsel fo hte lgali dan lrcauxllaerte rotie.mnvnen ehT ,lohiste -soipnmrneivse thwrog eennnoirtmv ,si ni rat,p reectad yb eht mtnaiorgi fo idytaesmsaneci-lo trnb,iohsii tcyasrost,e grloineoctoydde,s celyonogdtieord sruopcerr,s nad heT tvneminnreo tnwiih het NC,S seycaiellp lgfwonoil ,utraam tuernosccta hte reiapr fo nyelmi and tGwhor ractfso rea ont eexdpress or rerpxee-ses;d orf iacn,nset het etrxculaaellr tirmax si gakcnil smnniia.l lGila ssarc arlpyid r,fmo adn the ilag caylltau pdeucor crtfoas atht tniibih toalennyreiim dan oxna ;rriape ofr cnie,astn ONOG and 3-T5ehI.N aosnx mvhleeetss alos eosl the toentilpa orf owthrg tihw e,ag ude to a aeedsrce ni 4P3AG ers,nesoxpi ngmoa h.eorts

usmleuser007  (wiki) +  

submitted by usmleuser007(366),
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eeonetrorgnNarieu in het lipareeprh eosrnvu yemsts S)P(N ocrcus to a iasfgcnitni edr[6].e[5g]e ertfA an yurijn ot eth oxan, lhrieaprep uosenrn eiaavctt a vtyreia fo ialinggsn awpytash hwich tunr on rpo-gwrhto ,esneg leindga ot roetnoimarf fo a oltnfiacun gtorhw onec dan ognr.eeatneri The ogwtrh of tshee sxnoa si laso dereonvg by amictohctec aforsct tecsrdee rofm awncnhS slelc. junyrI to eht lrpeaiehrp oveurns stsyme tldeeaiymim islciet eht riiotgman fo ogsepathc,y nahwSnc lels,c adn achraopmseg ot eht nilseo etsi ni reodr to larec aywa sibdre hcsu sa daeagdm ueitss hicwh si hiniyotrbi ot ntaoengrrei.e ehnW a nerev xnao is rsd,eeev eth nde lslti tacdhaet to hte lcle dybo si albelde hte xalrimpo ent,msge elwhi het eohtr end si edlacl eht asldit .getmesn eAftr rj,yuni teh paoxlimr den sllesw and eeeipcnxesr meos gdreaotrre d,rgnoeaetnie tub neco hte rdsbei si eleadr,c it nigseb to rustop soxan dna teh peenesrc fo htrowg ncseo can be dcee.tdte Teh mioxlapr axson era leab ot geworr sa gnol as hte llce dbyo is tinact, nad tyeh evah aemd taoccnt with het nncwhSa llsce in eht elieodurnan aehncln ro .utbe nHuam oxan rtoghw arets anc hcera 2 mmd/ya ni mslla esevrn and 5 ymdm/a in realg .e4enrsv[] heT liasdt eest,mng v,eohrwe ereiscnepex Wnaillare taeneegordin hnitwi roshu of the rnjy;ui hte nxsoa dna imnyle ,egatdeener btu the neeirondmuu asm.iern In hte alert tgaess fo enoerinetrag eht imrennaig naerlonduei etbu ctsiedr aoxn ohtgrw abkc ot the etrcrco tgea.str rgniuD lnWraiela tein,erdenoga nhawSnc lecsl grwo in dodrere numolcs loagn the nieeoudanlr ,btue ngactrei a dabn of ügenrnB )b(Bo thta cpttreos and eevserpsr teh elnoaenrdui enlahc.n lA,os arpmhcegosa adn hcnSnaw ellcs eseealr pieothurnrco acforst atht heennac rgeot-rw.h


brotherimodu  That describes Schwann cells' involvement with neuroregeneration, but I don't see how it answers the question "Which cell is blocking reinnervation" +  

submitted by happysingh(40),
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ilealaWnr Drteeienoagn : oxaanl gaednrenoiet itasld ot tesi of sonecittnra + mloxaipr alaxon coatrenrti

ootAyxm olan(ax i)ottacennsr- of pipeaerhlr veensr rsluste ,in nwcnhSa esllc : .a nrakegbi ndow nyemil noit lsmal sagntfmre adn lefnsug bi t. uitnrricge hmaerapocgs to sseopid of oanlax idb rc.e ricngupod ohrtwg acstorf ot oretomp enretiergoan of nsoax