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NBME 22 Answers
A new virus has been isolated that causes ...
negative stranded can't be read by a translator so it needs to be transcribed into + first. Only then can it be used for protein. + is basically mRNA already.
There's only one double stranded RNA family as far as I know- Reovirus so no encephalitis
The only thing I can think of is that HIV is a (+)-sense single-stranded RNA virus that relies on an RNA dependent DNA polymerase (reverse transcriptase) to synthesize DNA.
according to [medbullets link](https://step1.medbullets.com/step1-microbiology/104196/rna-viruses_) ns ss RNA must carry RNA dependent RNA polymerase (so that is out).
also, according to medbullets there are very few ds RNA viruses, so "most likely" will be ss. Also, RNA-dependent DNA polymerase = Reverse Transcriptase. Since HIV is a ss ps RNA virus with RT, they've described an HIV cousin. not sure beyond this.
Can’t think of any retroviruses outside of HIV and HTLV and they’re both +ssRNA
"New" means made up fantasyland virus
Also Hep B is a ssDNA virus that goes to RNA, then is reverse transcribed to dsDNA