Caocbrni ardhyanse thorbsiiin g(e, o)timeclaeadza adn oplo iscriuted g,(e imusf)deroe are tgthohu to xeert tireh efectf no CIP by denguric lrcnariespobe fuldi F(S)C oucorpdtin at teh iohcrdo uplxe.s
ogloGe asys ehcainmsm si onknwun LO.L
Tish utenioqs mesak on essen ot .me Seh ash na lyeterxme wlo nienpog sesruerp yte ash nssig of aiensderc cilaairnntra pers.erus idD eyth amne ot tup 23 cm H???0?????2?
MedScape: "Acetazolamide (ACZ) and furosemide (FUR) treat posthemorrhagic hydrocephalus in neonates. Both are diuretics that also appear to decrease secretion of CSF at the level of the choroid plexus."
OH3-C is eedned ot mkae FCS. mAateeaidlzco bihsniti ccnaorbi sarneyahd adn edaecers 3OC-H bontaorips fmro arnel .betsuul
In patients with IIH treated with acetazolamide, the inhibition of carbonic anhydrase in the choroid plexus results in a reduction of CSF production and flow. The acid–base status of the patient may also alter the distribution of acetazolamide in the CSF and brain, but its effect on the CSF flow is secondary to that mediated by the choroid plexus. Based on the pharmacology and distribution of acetazolamide and carbonic anhydrase in the brain, the theory that emphasizes the effect of acetazolamide on CSF production in IIH is most likely primary and direct, and weight loss, when recognized as a factor, is secondary and indirect, and frequently the result of toxic doses in excess of the amount needed for complete enzyme inhibition.