NBME 24 E (NBME Answers)

need help with your account or subscription? click here to email us (or see the contact page)

Retired NBME 24 Answers

nbme24/Block 2/Question#23 (reveal difficulty score)
A 9-year-old boy who was adopted from an ...
E 🔍 / 📺 / 🌳 / 📖
tags:

+8 upvote downvote
submitted by ∗brethren_md(105)

get full access to all content ⋅ pick a username

Vitamin B12 is the distractor in this question because it also causes a broad-based, ataxic gait and decrease in vibration. But - Vitamin B12 will not have symptoms like Hemolytic Anemia (decreased hemoglobin, increased LDH). Vitamin E = answer, see below for explanation.

get full access to all content ⋅ pick a username

gonyyong Also the MCV was normal, not megaloblastic like you would see in B12 deficiency +8

+7 upvote downvote
submitted by ∗dbg(197)

get full access to all content ⋅ pick a username

WTF is "weakness of plantar dorsiflexion" ????? it's like saying "extension flexion" This is not the only obvious technical mistake in the new NBMEs ...

get full access to all content ⋅ pick a username

karthvee loool +2

yex Funny Board!! Yeahhhhh +

+4 upvote downvote
submitted by ∗karljeon(140)

get full access to all content ⋅ pick a username

Vitamin E deficiency causes hemolytic anemia, acanthocytosis, muscle weakness, posterior column and spinocerebellar tract demyelination.

get full access to all content ⋅ pick a username

karljeon Can anyone explain why the serum lactate dehydrogenase (LDH) level was elevated? +

asapdoc Vitamin E is an antioxidant. Thus a deficiency can cause hemolytic anemia. +6

sympathetikey @karljeon Intravascular hemolysis = LDH release from RBCs +4

+2 upvote downvote
submitted by aisel1787(6)

get full access to all content ⋅ pick a username

just for addition - here MCV is normal, in B12 deficiency it is high

get full access to all content ⋅ pick a username

+1 upvote downvote
submitted by ∗abhishek021196(119)

get full access to all content ⋅ pick a username

Vitamin E Deficiency - Hemolytic anemia, acanthocytosis, muscle weakness, demyelination of posterior columns (Decreased position and vibration sensation) and spinocerebellar tract (ataxia).

Neurologic presentation may appear similar to vitamin B 12 deficiency, but without megaloblastic anemia, hypersegmented neutrophils, or increased serum methylmalonic acid levels.

get full access to all content ⋅ pick a username

Must-See Comments from nbme24

seagull on Intestinal mucosa
tissue creep on Ask the roommate not to smoke in the apartment
drdoom on Adenosine
seagull on Increased serum testosterone concentration
atstillisafraud on Lamins
niboonsh on Only cookies are independently associated ...
atstillisafraud on Scar formation
lamhtu on Decreased adherence
drachenx on Damage to the rectovaginal septum
drdoom on Intestinal mucosa
azibird on Coronavirus
lsmarshall on Organic acid metabolism disorder
sympathetikey on Inhalant abuse
tea-cats-biscuits on Eosinophils