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NBME 24 Answers

nbme24/Block 2/Question#43 (27.4 difficulty score)
A 35-year-old woman has difficulty urinating ...
Parasympathomimetic stimulationπŸ”

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submitted by coolcatac(18),
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submitted by beeip(124),
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sniperx3  I think it's because Bethanechol acts on M3 receptors which can treat her urinary problems but it might exacerbate her asthma symptoms since there are M3 receptors on the lungs. +37  
suckitnbme  I definitely had to read this question multiple times to understand it. +2  
brotherimodu  I read it like 6 times and gave up +1  
motherhen  I definitely had to read this question multiple times to still not understand it +1  

submitted by sexymexican888(7),

I kind of just thought about the muscarinic antagonist treatments for COPD exacerbation and asthma

  • Tiotropium is a M3 antagonist used to treat COPD and asthma -> inhibits M3 -> airway dilation

  • There fore if an M3 antagonist dilates airways than an agonist such as bethanecol should do the opposite -> airway constriction (AKA parasympathomimetic stimulation) it would sorta be like doing a methacoline challenge pretty much