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Retired NBME 23 Answers

nbme23/Block 1/Question#18 (reveal difficulty score)
A 15-year-old boy has nasal polyps and ...
Enzyme B ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: biochem pathways 35

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 +25  upvote downvote
submitted by โˆ—sajaqua1(607)
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FA 2019 pg. 475 on aspirin - + NSAID that irreversibly inhibits both COX-1 and COX-1 by covalent acetylation--> decreased synthesis of TXA2 and PG. + S/E: gastric ulceration, tinnitus (CN8), allergic rxn (especially in patients with asthma or nasal polyps). chronic use can lead to AKI, AIN, GI bleeding.


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