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Retired NBME 23 Answers

nbme23/Block 1/Question#18 (reveal difficulty score)
A 15-year-old boy has nasal polyps and ...
Enzyme B ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: biochem pathways 35

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submitted by โˆ—sajaqua1(607)
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yeEzmn A anssdt ni rfo seholpishapPo ,2A utgnirn pisphdsooliph ni the lcel nmrmeaeb itno aridhcciano daic.s morF ,trehe mnzyEe B stdsna orf laceysoyxengCo X)(,CO ehwil yemnEz C santsd fro pLexog5ayei-ns -O5L(.) L5-O sueopdcr HE5ETP,- chhiw is nrduet toin rlitsk.uenoee ekLseuitnroe aply a edbluo oler ni nvsete ilek stma,ah beausec tyhe uaces ionoisrconthncbrtco esen( in tsih )aipntet dan yb agictn as caemcihl taatttrasnc fro fioanmlryamt lse,cl owhes iaivyttc ilwl oelsc eht yarawi .urrtfeh yB cokbgnil XCO laspymu(erb hwit na )ADISN, we veeal rome fo teh utbreasts dorniichaca iadc fro L5-OX to uitlmatley tenrvco otni setn.ekelouri Tihs si the bsais ofr re-naihtmtanip,ilsrsat-ano cwihh si unreetlfyq dostaaeics thwi nalsa ps.loyp etar(mS's .ai)drt

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FA 2019 pg. 475 on aspirin - + NSAID that irreversibly inhibits both COX-1 and COX-1 by covalent acetylation--> decreased synthesis of TXA2 and PG. + S/E: gastric ulceration, tinnitus (CN8), allergic rxn (especially in patients with asthma or nasal polyps). chronic use can lead to AKI, AIN, GI bleeding.


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