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lispectedwumbologist
That's so infuriating I stared at this question for 20 minutes thinking I did something wrong
+85
seagull
lol..my math never worked either. I also just chose the closest number. also, screw this question author for doing that.
+10
ht3
this is why you never waste 7 minutes on a question.... because of shit like this
+9
yotsubato
Why the FUCK did they not just give us a clearance of 0.1 if they're going to fuckin round it anyways...
+21
cr
in ur maths, why did u put 24h/1day and not 1day/24h? if the given Cl was 0.09L/hr/kg. I know it just is a math question, but iยดd appreciate if someone could explain it.
+1
hyperfukus
magic math!!!!! how TF r we supposed to know when they round and when they don't like wtf im so pissed someone please tell me step isn't like this...with such precise decimal answers and a calculator fxn you would assume they wanted an actual answer!
+1
jean_young2019
OMG, I've got the 25.92 mg/kg/day, which isn't any of the answer choices listed. So I chose the D 51.8, because 51.8 is double of 25.9......I thought I must have make a mistake during the calculation ......
+7
atbangura
They purposely did that so if you made a mistake with your conversion like I did, you might end up with 2.5 which was one of the answer choices. SMH
+7
titanesxvi
I did well, but I thought that my mistake was something to do with the conversion and end up choosing 2.5 because it is similar to 25.92
+4
makinallkindzofgainz
The fact that we pay these people 60 dollars a pop for poorly formatted and written exams boggles my mind, and yet here I am, about to buy Form 24
+23
frustratedllama
Not only do you feel like you're doing sth wrong but then that feeling stays for other questions. sucks so baad
+1
fexx
'here.. take 50mg of vyvanse.. I just rounded it up from 30.. dw you'll be fine' (totally doing this with my patients 8-))
+1
cbreland
I was so close to picking 2.5 because I thought I did a conversion error. 5 minutes later and still didn't feel comfortable picking 28.8๐ก
+
yesa
12ug/ml = 12mg/L; 12mg/L x .1L/hr/kg x 24hr/day = 28.8. No need to multiple numerators and denominators by 1000s
+
chaosawaits
What really grinds my gears is that 3/5 answer choices are closely related to using 0.09 instead of 0.1 (A is 25.92/10, D is 25.92*2, and B is D/10). So basically, we're supposed to know to round 0.09 up to 0.1 but also to not round 12 down to 10. Okay?
+
impostersyndromel1000
so you're telling me that I did all my math correctly, got 25.92 then thought I was off by a decimal point and chose 2.5 bc 25.9 wasn't an option and I was actually correct in my math but wrong bc THEY DIDNT PUT THE RIGHT ANSWER? Why is NBME so trash? I hope real exam isnt this bad.
+1
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tyrionwill
When I got 25.9 and found nothing exactly matched, I guessed that the maintenance dose might be a bit more due to the bioavailability. So this antibiotic probably was not an I.V. formula, but an oral one, with a roughly 90% BA.
+2
eradionova
Well then it could have been equally likely that it had a 50% BA and the answer would be 51.8 exactly. I almost considered picking that but in the end stuck with the one that was closest to my answer lol
+2
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veryhungrycaterpillar
Oral antibiotics for septicemia? None of the Step 1 question writers are medical doctors, so this actually makes sense.
+1
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faus305
Don't skip it but flag it, give yourself 1 minute and 30 seconds or less to figure it out and if you don't then move on and come back if you have time.
Questions like these are what I like to call "time wasters." I got it wrong because I selected 2.5 assuming I made a conversion error when I arrived at 25.9 as my answer.
I think the lesson to learn here is that 28 is closer to 25 than 2.5 and NBME are evil people that know I'm not gonna make a conversion error. If you do math in a question and you are SURE you did it write, select the answer closest to the answer your math got you.
+
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mousie
Equation is Maintenance dose = (concentration at steady state) * (Clearance)
if you convert all the units to what it wanted them in (mg/kg/day) you'll get 25.92 like weird-in said above
I didn't think to round 0.09 to 0.1 of course so I guessed 2.5 assuming I must have done a conversion wrong and was off by a tenth .... BOO bad Q
+4
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submitted by โwired-in(81)
Maintenance dose formula is
(Css ร Cl ร tau) รท Fwhere
Cssis steady-state target plasma conc. of drug,Clis clearance,tauis dosage interval &Fis bioavailability.Neither dosage interval nor bioavailability is given, so ignoring those & plugging in the numbers (careful to convert units to mg/kg/day):
=(12 ug/mL ร 1 mg/1000 ug) ร (0.09 L/hr/kg ร 1000 mL/1 L ร 24 hr/1 day)
= 25.92 mg/kg/day
...which isn't any of the answer choices listed. They must have rounded 0.09 L/hr/kg to 0.1 L/hr/kg, and doing so gives exactly 28.8 mg/kg/day (choice C)