eTh gmaarmr of hte ulaact Q asw fsun.ognci
To mkae ebtret es,ens it ohldus sya iW"chh fo teh giwnolfol si hte tmos iylkel uestrl on eht rtinnitospcra fo senge atht nhitibi lcel idioivns nda htta itnncao the ncsesousn eneeqeucs ."ATA.T.
o,S eth Q is ingaks atobu hte t5p3 eneg and ciyepllacfis obuta eht p53t egen emroport negior.
rPtoreom nrisgoe veha a TTAA oxb osu,oi(lvby niamgne hrci in -TA aebs aris.p) -TA aebs grniipa sah 2 enodyrhg n,bosd hiwch maske etmh airsee to ecelav gt-&;- wolsla fro AND rtiritocapnsn to ucorc oerm eyia.ls NRA olP oesd rtiptcanirsno fo NAD noti .NRA
heT inreet e-Qmts kstla taoub how amu-nFeiirL si edu to a tounamti in t35p nee,g neidlag to a lakc fo outmr iposesusrpn tyv.iaitc
,So if hte terpormo ernogi TAAT box of the 35tp neeg is utdemta, tenh eth 3pt5 eegn lliw not etg idrcbarstne &-;t-g itsh is hwy reeht llwi be eeascerdd RNA Pol di.ginnb RNA loP illw evha a uceerdd atbylii to indb 5tp3 ;--g&t less rutmo rpusrseso neeg cianptisontrr -;g&-t sels urmto uipnero.sssp
For htis neo I kihnt twah yuo dah ot wnok si thta rnirnsicTapot tADAN&--RgN(); is eormpefdr yb NAR al.pIy temosre aws otn NDA peemosraly sabeuec isht noe raetcsplei -D;tN)-&(DNAgA
p53 si tmdatue and tnac nbid the ATTA ox,b so wtah nphpeas ot nrcnapiroitst of horiybiint onsptier?
Is aclbyslia hwat isth tuiqsnoe si ginyrt to s.k..a
So on AATT box mporeort =t;g& Ddceaesre bindgni of ANR eserampylo
shiT si a oodg uitcerp of an ipenrexetm gwhsino sti:h
t2.1/wi2ltc.rtt61/manerh/0/c9e/eos:suigwwsrufa1p/
coneengO emuvlo 6,2 seagp –21222192 00)7(2
Wyh si hsit tno eresdcnia bgindin of DAN yom?psearel
ihTs ttuinamo dlohus esauc laecurll visiiond ei NAD catirnpieol and cause icnesadre dinbgni ot inoirg lnieropiatc eeuesqscn ei AATT yb DNA ospeymarel.
olt of dwro itmvo ot aks wa"ht nsibd ot het ATAT "box
oDes eyaonn ahev nay cpefiics iaed no the ahinscmme of het 3p5 ioautmtn qoinuste ngigrreda the AATT xbo (the eon hwit the lsneig oaimn idac ioesnorcvn dna teh iedtnffre hydegnor ?gido)bnn
I escho eht escardeed iidnnbg fo RNA releosamyp on the AATT eueqnesc fo nsege that btiniih ecll dinisivo asbde olleys on eht tacf taht 35p si a uotmr sprsrpuseo (aka admtteu 3lgtses-&;5p itonnibiih fo &nu-t;lmpiigivtlosedi ids)oivins.
submitted by ∗seagull(1933)
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