need help with your account or subscription? click here to email us (or see the contact page)
join telegramNEW! discord
jump to exam page:
search for anything ⋅ score predictor (“predict me!”)

You must be logged in to vote!
Retired NBME 24 Answers

nbme24/Block 3/Question#46 (reveal difficulty score)
A 15-year-old girl with cystic fibrosis has a ...
Endoplasmic reticulum 🔍 / 📺 / 🌳 / 📖
tags: cell_bio cell_transport cell_trafficking protein_folding

 Login (or register) to see more


 +7  upvote downvote
submitted by vshummy(184)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$379$49

I nkhit emor nyeaerllg, tnpoeri dflinog espnpha at eth RRE dna eth esmt ysas teh ntipreo de’ntso lofd prypoe.lr llcpyefaSci,i hte stmo cnomom FC itotuanm si a elimfosdd ntoirep dan het nperoti is ertaiden in the ERR nda nto enptdtorsar to hte lelc mmarneeb - AF 1092 pg .60

unscramble the site ⋅ become a member$379$49
uroosisyed5  hiWhc kemsa seesn if ew hintk outab eth hpsoyhtap of eeedavtl C-l dan Na yeurll.rlalaictn hBto of heets nios go up eiidsn teh clsel edu ot the irttnoeen fo the osddefilm osnrepit in het RER. +
lilyo  I atucllya isdeager tihw isth gnenrioas. eTh yhoogslptophayi in RTFC is ont due ot cumaioacnutl fo ilsdedfom sertonip. It si edu to nee/decbadrtsaes PAT gated tnbaenemmarsr iCoedlrh n.anclhe rodgcAcni to r,oldwU het dmsicode tinreop si dteetedc yb teh lEonpdaimsc .cmetuRuli The rlnamoab etonipr is tdteearg fro uneotrtsdic by eht omtoaerspe nda veren raceshe the elcl ceuafr.s ehreT is NO enritoent of edfoilmds ,epintro rehet is nogiaddrtea of esoifmdld tpnreio and errotefeh cneaseb fo doehcrli ahnnlsce on eth mnaer.meb Tshi is tahw leasd ot mpraiedi oavrmel of satl fmor het twaes as elwl sa erdeedsca lNCa in msu.cu I dtno tihnk the anersw losuhd eb .RE aCn anoeyn ltel me if I am igmssni snoitemhg ereh ahtt ekams eth warens ER sa dpooeps ot oamcslp?ty ueBcsea eht way I see if is fldsdmoei oprienst og ormf eth ER niot eht mcsplaoyt to echra het mtepsaoroe dan hten be dedc.erttus lwdoUr tnsosiequ DI ear ,058 208, 1,145 nda 3.991 +19
drdoom  lioy@l hTe RFCT si a nbmearnmtreas it.penro Liek lal eispo,rnt ist sarnolantit einbsg ni the ;sootlcy hatt said, RFTC itnnasoc na uiesr-nNmt isl“nag eseu,cnqe” chiwh esman as ti is bigen tldesna,tra it (nad hte msbeoiro aigmkn ti)! illw eb tsoadetrpnr to het moEcdaplisn utniee^!uootfc.Rlotm As ti gtes dta,rtenlas its cohryobhdpi tofims wlli germee, hcwhi dbseme het FCTR oiptenr iniwht eth ppdihphslioo bleyair of eht RE lfe!its aTht neams hte roetpin illw eenvr iagna be ndfuo “in teh sclyto”o easuecb it gste dherdeat grtouhh eht beiyarl i(hwhc ,si in fc,ta owh lla mbsnanetmrera nprisoet mceboe nbseretmnamar spntrieo at teh ellc uersfac -- yhet ahev ot be eadm itno msanerartmnbe otnrpesi in eth ER srif.!)t +11
drdoom  oll@iy duonnc()eit oS, y,se it,elmlyatu stehe dsiedmolf otnreisp lilw eb tredecid wtodar a peosetmaro fro adoyr/ac,tngirglidceen tbu taht llwi ahnepp as a tletil ilsvece r(o ioomp”);ls“e teh ifslddoem trni,ope ni htis ca,es is not se-wallrbueot e,(nics by idif,itonen it has obdochphryi tsfomi hwich teg dahte“der hgtro”uh a ebraiyl ot ceater the msaaeebmnntrr tp)tan,re hhciw senam uoy ont’w dinf ti ni eth s.ylootc +6
drdoom  !foeto^nto : hTe evmtenom fo ieac*vt mboeoriss rofm eht styoocl ot the imsponlEdac lueRimcut si yhw we call atht eara fo RE uorh“g niapslmdEoc iuctmRule E;”R()r no enelrcot yio,cosrmpc ttah ntiecos was lpkecsebed twhi lelitt stod; ,tlear we ns(ha)um rdoidvcees that sthee sdot rewe sbiosrme!o +1
drdoom  * yB veat“ic osibo”,serm I utsj amne bsriosome ni het rcposse of rgnvtcione RmNA ot triep!no ht(aW we call otsan“litna”r ) ; +1
wrongcareer69  oHw many nmadogd wysa rea hety iongg to tets su no .FC 'mI so oerv i!hst +2
furqanka  osla in ,AF urend aphla 1 tatsinyrip,n its asys Md'lesodif gene pocrdut topnrie gggerteaas in uceplelaartlho E."R gmtih eb eht emas n.ccpteo +9
joanmanuel26  Airconcgd to pal;Kna llA ernoipts ttha are tdeeynhzssi in teh ER stum dlof ryorcetcl in orred ot eb eprtsrotdna to hte oiglg putaraas adn ethn ot eithr failn tsdsneotai.ni fI eht mtautnoi cseua a feddlmsio ,tipnero hte truesl wlli be the loss of eht iopnrte tinfnouc nd,a in soem sas,ec lnatuaimocuc fo eth ieprnot in hte ER. +1
drdoom  ol@ily kininhgT atubo hist eorm. ouY lilw ont difn hte (flmddis)oe otieprn in the looc.syt hTe omdilsefd oipntre may eb siedni a —pemndateasoro a sorotaempe mya evil ni teh costbuy—tol the imoeddlsf pinreot lstfei lliw nvree rppaea ni teh ctoslyo. The usctrdpo fo tis tadiodngrea mtihg eou(ntittsnc ainmo iadcs or llsam pe)diptse btu if oyu hda an bytanodi rof eht somdifeld iptrnoe dna esakd ti W“eehr si het emdlisfod ,tn”ieo?rp eht dotnyabi owldu we:srna tos“M fo twah I ulcod fdni praespa ot eb ni the rR.E” +
yesa  hcekC otu eth lniancex c,ycel ayusllu onrispte ahtt ear aemd in teh ERR and dfidmosel get tgaegd nda 'eldf'erdo adn nthe nsendca naaig fro prorpe ino..d.dnflga if hyte alrely c'nta eb eforledd, 'yreteh rdgdaeed nhte adn !hreet oS het nloy aecpl eodsimfld FRCT dclou cemaauctlu if msilddeof R...sR.i.E.. k(iLn to encxinal lccye: cmgLtihtp5=YmEb2U&ei9sIky&/=tMm1ogefseo2jD/=0aaemHPrCg&;+paAp=ZUlscsrRp=Ua.pwe;X18H=&AxV5hcwiwB48siCp1n;cWbhm5&mmghdciQ8tQm&a83ro;jOe:/bXBsFr2vDoOK5I9pu2r=7=0Uplr+hajAYTQa?6e9al7hI_QabqQgi.e4mg&03ahagUwm;=oKxuaIAss81L7hwa;7:ZAvwKDr;MnEmVH#os4) +
amy  2F02A0 7:4 " sAnbte ro aocsnfuydlnti RPS sanlig( oercnitgoin taerlcpi) lrsuste in uoacnimatucl of erpnoti in eht clyo"sto +
drdoom  @,yam thsa’t a ogdo oipnt utb it smsaeus teh ietnrpo is hsreeiowt laormn, ..ie, nto fsddlmeio ro mao“l”barn ni meos etrho ywa +

For a great little summary of the Endoplasmic Reticulum (and many other concepts in molecular biology!), see this from Alberts’ Molecular Biology of the Cell: https://www.ncbi.nlm.nih.gov/books/NBK26841/#A2204

+/- drdoom(1206)

You must be logged in to vote!

 +4  upvote downvote
submitted by seagull(1933)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$379$49

I eahv na ussie ihtw hits tenoqisu which oals sicntoflc hwit WldU.ro nI eordr to eb adeergdd by pesosromote hte dofsdeilm ieopntr luwdo ende to eb sneetrp ni teh ctosloy for uibntiau.on tI it uaeulccmdat ni the RER tnhe how sdeo ti etg eagdg?t ,styeonHl os lctf...ineodc

unscramble the site ⋅ become a member$379$49
sajaqua1  oS rioanriydl a ofidmdles rotipen dseo gnuored ionqibtuniitua nda oeoytils.rps tI si abnoelet that RTCF odsmigfnli 'sdotne eevn lawlo ti pesaec the R,E so it caulsateumc ni eth ER +9


You must be logged in to vote!

 +4  upvote downvote
submitted by drdoom(1206)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$379$49

Teh TCFR eoirtnp si a mrnaenbmtsare rnpto.ie keiL all reint,pos its oanirtltans sginbe ni eth o;oslytc ahtt dsai, RTCF aitnnocs na -ensiNutmr galnis“ esne,cqeu” hcihw semna as it si bnegi leas,dnrtta ti (dan hte ibmeorso iagmnk !t)i lwli be astopterrdn to teh dopaElnmsci ic^uRumelt.ofeo!ntto

As it segt ntdata,rsle sti oprbhcyiohd otisfm liwl ,gemeer hciwh sdmbee eht FRTC nrpteoi itnwih teh sphidpholpio ilybrea fo the ER if!elst Thta nesma het eoitrnp lliw rneve anaig be oufnd “ni het cyoo”stl euescab ti gste trdeahde hrgthuo eth raieylb ihwhc( ,is in tfa,c who all armmtbrnsnaee rstnopie ocmeeb emearsbnrmnta oesnrpit ta the lelc reafsuc -- htey haev ot eb eamd oint ebarmsntamnre entsroip ni teh RE frtsi!.)

So, e,sy tye,lmiltau seeht moilddfse perionst lliw eb eirdedct aodwtr a otpmeerosa orf ,itagcyeroilnndgd/aerc ubt that wlil phpnae as a ttlile ilseecv r(o mpo;“e”losi) het esldidfom ,etrinpo ni siht aces, si not tsre-alluewob sen(,ic by idoinf,enti it ahs hyoircohdpb smtoif hihwc egt hda“eerdt trg”ouhh a yalerib ot cetear eth anebmmarsetnr n,tr)apet hciwh nmase yuo tn’ow dfin it in teh cs.yltoo


\ oettonf!o \ The cginihht fo iavc*te mbsseorio to het ndpocEsmali iRetmuulc si hwy ew lalc htat area of RE “huorg conpslmadEi iuetmculR (;)”RrE on lerncote isopcromc,y ahtt intesco swa dlsbecpeek htiw ttilel ;stdo ter,al ew nhau()sm sidedveocr thta heets sotd erwe miooer!ssb

\ * \ By tvciea“ b”oosmsire, I jstu amne omirsesbo ni het erscops fo ciogenrvnt AmRN to tipoe!rn Wha(t ew clal oi“tnastal”nr ;)

For a rtage liltte musraym fo eth dimcEnspaol eRlumuitc adn( yanm ohert ctpoesnc in lemucoalr )oboyi!g,l ese this ofrm A’rlbtes llceoauMr igyoloB fo hte lleC:
h.Anowwnbb84/g0s/.kl1:Koi#pNs/.t2/mw2/n4ocBthi2.v6

unscramble the site ⋅ become a member$379$49
drdoom  ^ I'm sjut ntgiatres- ni eno cmmnteo twha I roetw ni tuimllep msomcbensut vebao: 9:te/n1m/psne7s./r/se/99#mmtebaoa33hwbxc4mn2 +

A mini-discussion of protein transport within the cell is here: https://nbmeanswers.com/exam/nbme21/742#257

+/- drdoom(1206)

You must be logged in to vote!

 +4  upvote downvote
submitted by therealslimshady(42)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$379$49

hWen epsiontr egnbi made in het ER ,ldomifs eyth cealcauumt in het ,ER whhic hnte egsirtgr emht ot be pits tuo toni het oloscty and coembe garededd by operts.asemo T,hus the inamluctcoua fo eht siflddemo iontepr in het RE si rriequde rof htme to ayeilmttlu eb gegdta yb qiuubniti adn be edddgrae in r.mesostaepo

Enev if you eagru atht heyt lwil be nicctalagumu ni hte oyoctls uesbcea eesraosptmo era in hte ocsoytl, eth sntquoei si sakign hrwee aer eht toiprnes munauaigtlcc, otn gbein aededrgd. So yteh c'tna lectuaaumc ni emsasporo,te eebusac htey era drodtseey in .etmh

unscramble the site ⋅ become a member$379$49
drdoom  inec hcact htwi het amca“nglit”cuu ea!rrkm q,q nehw oyu ysa grrgts“ei htme ot eb ispt tou toni the os,otycl” od yuo veah a rucose ofr ?tath don't carlle relinnga htat weheayrn sfylm.e htx! +1
therealslimshady  I nta'c rrbememe hwree I rdea hsit ubt ti utskc iwth em, I nhikt ti saw a elcl iob kboo +


You must be logged in to vote!

 +1  upvote downvote
submitted by mutteringly(34)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$379$49

iTsh is rfom sbsa:mo tedaMut FTRC eneg 580ΔF( tm)tionau → omsdidfel nepoitr → ctdevieef eoirtnp si tenderai in hte ghour dmcoepilnas imreltucu R)r(E for rnotiadegda → PT-Aadteg hiedlroc ahclnen si esnbta no teh clel rasuefc fo llpeiaieth lscel hrughotout eht oybd ,..e(g senatinitl dna rsoaietrryp ,atplieieh waset ald,gsn ceeiorxn nre,spcaa excenori andlgs of ceroeiptdvru ogrs)an

unscramble the site ⋅ become a member$379$49


You must be logged in to vote!

 +0  upvote downvote
submitted by unknown001(9)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$379$49

RTAUL IS.MEPL

hree1t. rae amyn rstaaivn fo scyict boifisrs so hsti eusqtino is ton utaob hyp.yaspht fo CF

ino2.tp fo ineutoqs : hewre dose tonprie ofindlg ocruc ? rnwsea) RRE

  1. NI TSHI TPYE FO FC , fi otepinr onsit lfddeo rppyoerl in RRE lilw ti go tuo or lliw it aceatcumul ? nwesa)r ti llwi euctlumcaa ni R.ER

PIT : FI OUY KEPE ENRSGERIAHC NO ATIASVRN OF F,C YOU REA NO A PHTA TO ESLSEDN OMDO

unscramble the site ⋅ become a member$379$49


You must be logged in to vote!

 +0  upvote downvote
submitted by blah_blah(1)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$379$49

epul hfl?blIuwaw3watHeftjnuit.ythyhyoh/cansplNme&sp/ociQBnwXcm;u/ooe_.=bvsaga:gG=

unscramble the site ⋅ become a member$379$49


You must be logged in to vote!

 -1  upvote downvote
submitted by welpdedelp(270)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$379$49

ib/i04o=83nHntT_Pesms/97_/1kn5g:2v0_eC4hdysLo2.5./5ep8h1i9M2n5agr339gt.p29_.s///0F2cp1ls1n13w2i_e?M22ogm

unscramble the site ⋅ become a member$379$49


You must be logged in to vote!

Must-See Comments from nbme24

seagull on Intestinal mucosa
tissue creep on Ask the roommate not to smoke in the apartment
drdoom on Adenosine
seagull on Increased serum testosterone concentration
atstillisafraud on Lamins
niboonsh on Only cookies are independently associated ...
atstillisafraud on Scar formation
lamhtu on Decreased adherence
drachenx on Damage to the rectovaginal septum
drdoom on Intestinal mucosa
azibird on Coronavirus
lsmarshall on Organic acid metabolism disorder
sympathetikey on Inhalant abuse
tea-cats-biscuits on Eosinophils

search for anything NEW!