need help with your account or subscription? click here to email us (or see the contact page)
join telegramNEW! discord
jump to exam page:
search for anything ⋅ score predictor (“predict me!”)

You must be logged in to vote!
Retired NBME 24 Answers

nbme24/Block 3/Question#46 (reveal difficulty score)
A 15-year-old girl with cystic fibrosis has a ...
Endoplasmic reticulum 🔍 / 📺 / 🌳 / 📖
tags: cell_bio cell_transport cell_trafficking protein_folding

 Login (or register) to see more


 +7  upvote downvote
submitted by vshummy(184)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$379$49

I hintk orem aellreyn,g erptnio difgnol epnapsh ta hte ERR nda eht smet says the rointpe td’nose lfod le.prpyor pilleaciSfc,y teh stmo mocmno FC mtoaiunt is a fmdoiedsl oipetrn nda eht eptiorn si ateidren ni hte ERR dna not atpetsdnorr ot eth ellc emabmnre - AF 1209 gp 0.6

unscramble the site ⋅ become a member$379$49
uroosisyed5  hcihW akmse eesns fi we tnihk tbuao eth pytsaphoh fo taelevde -Cl nda aN tlar.rcualleylin ohtB of ehets snio og pu iinesd the lecsl ude to hte ireetnotn of hte ddlsmfieo pestroin ni eth R.ER +
lilyo  I aalctuyl edgsriea hiwt itsh nrg.isaeon heT hhpoyooptslgaiy ni CTFR si otn ude ot ntculcaaiomu of esdmlfido ro.etpisn It is eud ot cdbatarssedeee/n TAP gteda nbtameamnsrer ildoehCr enan.lhc nocrAicdg ot lrU,dow eth smcioedd renopti si tetdeced by the imcEasponld uRmuec.tli heT orlnabam onietrp is ategtred rof rudeocsintt yb the oorsepemat dna never srhecae eht clel sreaf.cu eTehr is ON ninoertet of sfmdidoel i,peotrn ehret is tdareinodag fo dsmidoefl eprotni nad fereerhot aecsebn of ciorlhed scanhenl on het aeen.rbmm This is athw aesld to riepadim movelar fo satl mrof the ewast sa ewll as aeersedcd laCN in u.scum I notd thnki the ernwas lduohs be E.R aCn neanyo tlel me fi I ma imsigns htsneomgi here atht kmeas teh arnesw ER as opsodep ot s?mtcpoayl eseuaBc eht ayw I ese fi si dilsdmfoe piotnesr og mrfo hte RE oitn eht cypmatlso to ahrec teh eptoaesmro nad enht eb dceudsertt. wodrlU isuesoqtn DI are 850, 028, 5411, nda 319.9 +19
drdoom  i@olyl hTe FTRC is a aertnesmabmrn on.eprti iLke all tsnoi,pre ist aitnslatonr nigseb ni eht otl;ysco hatt iasd, FCTR intonsca an stNne-ruim gsa“lin ”esnueqe,c hwcih samen sa ti si nebig r,adsettnal ti dan( het siormobe agmink )it! lwil be drtepranost to hte lsaimpcEndo Ru!fooec.liettumo^tn sA it tesg nsdr,talate tis pboryochhdi ftmsio lilw gmeer,e hiwch besdem het CFRT nrpiteo inwthi eht hopilipphods iabreyl of eht ER slitf!e ahtT nmaes eth neptroi wlli vnree ainga be onfdu n“i het ”ocsoytl aseecub ti gest etdedarh rouhtgh the balirey ih(chw si, in f,act ohw all nrrmsmaetneba irpnstoe boecme asernertmnabm ioenrpst ta eth lelc fueacrs -- etyh ehav to eb made onti aernmsrnatbem serpnoit ni het RE r)st!.if +11
drdoom  oliy@l tic)ond(uen ,So ,sye y,ltmtueali hetes lmsdeifod pnreotsi illw eb ecdietdr watdor a semoretpao for anae/dytlcriogc,rdngei tbu ahtt wlli naehpp sa a ltilte levcies or( ”op)sloe“i;m the oflmeddis rnpie,ot ni this ,ecsa si otn erelabtolsuw- ienc(,s by fdtiiennio, ti hsa hprodibochy stifom hwcih get heaedrt“d htorh”ug a elabyir ot erecta het ntramnbearsem ntapte),r cihwh aesmn uyo wt’no ifdn ti in teh t.yosloc +6
drdoom  onf^o!toet : The tmevomen of itceva* obssmiero fmor hte ylcsoto to het dacnspmElio tiulcmueR si why ew allc htat raea fo RE rohgu“ anlmospicEd iuetulcmR );r”(ER no lncotree prciom,scyo taht tisocen was pbedsckele htwi lilett td;so lr,ate we s)mhnu(a erivdedsoc htat ehste sdot rewe emsi!orsbo +1
drdoom  * By ivect“a ”imesos,obr I utsj anme msoriosbe in eth csoprse of ovrcnitneg ARmN to !otripen W(hat ew lacl nno“alaris”tt ); +1
wrongcareer69  woH ynma anmodgd yasw ear htey ngigo to ttes su no FC. I'm so oevr ht!si +2
furqanka  asol in AF, nedru ahpla 1 srnpyitinta, tis asys Misld'deof ngee crtopdu poienrt eartsaggeg ni catueoplhaellr R.E" igthm eb eth sema pntoe.cc +9
joanmanuel26  cnrdcAgio to ;pnKlaa llA rosniept thta era nsthzidesey ni the ER smut dofl rroctlyec ni oderr ot eb otntsprread to teh ggilo rspataua and ehnt to ither lianf atsniends.oit If eht tonuatim aseuc a mlddioefs pne,roti eth sulter will eb het slso of eht epntior fnutinco ,dna in smeo sca,es ccilunmotuaa of het reipotn in teh .ER +1
drdoom  lil@yo nnkiTihg touba this rome. uYo will otn fnid teh dfmsldoie)( pertoin in teh oyoclts. ehT eldofmdsi reopnti yam be siedni a pmde—aernoosat a rsmateoeop aym liev in the yblutcotso— teh lsdiedomf netipro ilefst llwi rneve ppeara in het s.clytoo Teh dtrposcu fo tis rdagtainedo imthg ntneto(ustic naiom isacd or lsaml sdi)ptpee ubt if you ahd na tyiodanb rfo eth smieoddlf inporet adn akdes it W“rehe si the oidfsmedl ot,ep”ri?n het bnaytido dulow sw:rena Mt“os of tawh I cdulo fidn saarepp to eb ni teh rE”R. +
yesa  cekhC tou het ncainxel cl,eyc yusulla inserpot taht ear adem in teh RER dan ddsefmlio gte dgetag adn rdofleed'' dna ethn endscna gaain for prerpo .li.nadof.dgn fi eyth llyrae cn'at eb efdloe,rd tyh'ere dgeradde hnet dna !theer oS the loyn cpale eilsdmdof CRTF could ceulcaautm fi idomdslef ER.sR....i.. iknL( ot lancienx c:eycl Zj01289lr0mAH&MFemLrAYacUtaKvQU4Q;a./eQjhuUoioMiD.43a&qIwat=hi;:gmpX4gpgOy1Ts?V9&pIpUAXCm&ohm8hKB:hm&;cUpHsQr8D6=pAretObnpIm0jRxaQ7iew12WPs=s3I;g2sa7mm+e=AEpb;gZwaa8b=7rCmgksobgiVws=;Hieh/dot&r=5rs5=nasDhY/a9&lwc1Emv72+hee#c;5x8KlLu=wB5aafo_c) +
amy  F0A220 74: " bAents or uinlnsytacdfo RSP ns(agil ngcortnoiei cirtp)ael tlusesr in anuiamcotucl of oetnrip ni eht loo"csyt +
drdoom  a,@ym sh’tat a doog opitn btu it ssuasem het itreonp is eshetiwro ,mrnola ,..ie otn sdfdmleoi or moba”“alrn in eosm herot awy +

For a great little summary of the Endoplasmic Reticulum (and many other concepts in molecular biology!), see this from Alberts’ Molecular Biology of the Cell: https://www.ncbi.nlm.nih.gov/books/NBK26841/#A2204

+/- drdoom(1206)

You must be logged in to vote!

 +4  upvote downvote
submitted by seagull(1933)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$379$49

I heav na siuse ihtw htsi usqtoein hwchi oals fiotclncs wthi Udo.rlW In reodr to eb ddeaedrg by moopoesesrt the dlidfmeso ronpeit ludow eend to be eentsrp in eht tsyoclo rfo .ntouabiiun It it tcucaueadlm ni teh ERR nteh who esod ti etg getgd?a ytloenH,s os ti.nfc.ocl.ed

unscramble the site ⋅ become a member$379$49
sajaqua1  oS nloiydrira a lodesdmfi neptori odse uorgden iqnbuititinauo nda lti.yersospo tI is tenlbaoe thta CFRT sgldfioimn eosdt'n nvee alwlo ti cpseae eht ER, so it amsuuaetlcc ni eht RE +9


You must be logged in to vote!

 +4  upvote downvote
submitted by drdoom(1206)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$379$49

heT FTRC prineot si a marnnsaebmret pinreot. kiLe lla ,etsipnro ist tnlaotrsain gneibs in the ooslt;yc atht dai,s CFRT icnsaotn an uts-rneimN gsia“ln ,en”uqcsee hhiwc mesan sa it si egbni l,teasdantr ti da(n eth irmosobe kimagn ti)! wlil eb danopresrtt ot the Emdispnlcao R^lu.miutecoeofn!ott

sA ti steg atrtsaenl,d sit cdpbhiorhoy oismft wlli eeremg, cwhih ebdmes eth FTRC nirotep tiiwnh hte ldpihpphoios rbiayel fo het RE s!etlif Thta emans het nportei iwll vener nigaa be dnfuo “ni eth lsocoyt” escebau ti etsg etrhddae guhohtr the ayrebli h(cwhi i,s ni ctf,a ohw all bmnesrramtaen iprsoetn mcoebe mtrsraebnanem pseoirnt ta eth clel cufsaer -- eyth ahve ot be amde inot nbmenamstaerr ietrnspo in the RE i)!frt.s

,So sey, utalmitl,ye tehes fdioesdlm nisrtepo lwil eb dctriede adrotw a esomraetpo for ,ndneaateocrdigr/ilycg tub that illw nhappe sa a ttliel isceelv or( o;“s)ipl”moe eth emifldods ripteo,n in sthi a,ces si otn -brauetlwelso eicns(, by dnoiiitfen, it ash oriyhodbpch motfis cwihh get ehde“dtar ”grohhut a airebyl ot arteec teh anrbaemenstrm )aprn,tet hwchi smena uoy wto’n dinf it ni teh otl.yocs


\ oon!tofte \ heT hihgtinc fo iaecvt* sosermboi to eth oEldsmicapn eiuumltRc si wyh ew clla atth eraa fo RE r“ohug pEmlodaicns tueiucRlm E”;(R)r on enrctleo mpriccsoo,y tath tnesoci asw eskbeelcdp whti ltilet ds;to aetr,l ew m)(sanhu cidesvrode ahtt tehse osdt ewre risoemobs!

\ * \ yB vci“tea oeisrombs”, I sutj neam rioobsems in hte porsces of nnrvtoegic RNmA ot !eripnot Wth(a we alcl at”tnais“lnro );

Fro a eagrt ltteil srmamyu fo hte pdoilmaEscn etcluuRim d(na anym htreo sncocpet ni mlluocera ,!goi)bloy ees stih mfro lsrbA’et ueocalrMl glyooBi fo teh Cell:
#6vihtin0w:/4mw/t/./2/nwNbnb.8..ssh14KoBgp2A2cookl

unscramble the site ⋅ become a member$379$49
drdoom  ^ mI' tusj t-isretang in oen cmnomte hatw I wotre ni ltmpileu tsnmecsmubo ob:vea .bmnwa///hnm2p/csoem37/e#nr9xm9sb3s1ta9e4e:t +

A mini-discussion of protein transport within the cell is here: https://nbmeanswers.com/exam/nbme21/742#257

+/- drdoom(1206)

You must be logged in to vote!

 +4  upvote downvote
submitted by therealslimshady(42)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$379$49

nWhe nietrspo geibn aemd ni eht RE d,lifsom thye alcuuamtce in the ,RE hwich tenh rtgrgsei tmhe ot be sipt otu tnio the ocostly nda eomecb ddeeragd yb s.oroeatemps shuT, eht uouitalcmcan fo het dloedsimf opeinrt ni teh ER is rreeuidq for mteh ot miettually eb gdtaeg by iibnuquti and eb gdaeeddr in rp.aosetemos

nEve fi uyo graeu thta yteh illw eb aaglccitunmu in teh syoclto subeeca eptemssoaro ear in hte ty,csloo the eisnutqo is ngiask wheer are eth tireposn mncaciuuaglt, tno geibn gddeader. oS yeht acnt' tumacaceul in etprsamos,eo ebasceu ehty ear yeosdterd ni t.meh

unscramble the site ⋅ become a member$379$49
drdoom  icen atcch wiht het alccm”niug“tau rkra!me ,qq when you say ir“tggsre emht ot eb pits tuo niot the ”cys,olto od ouy aevh a uecosr fro tath? todn' allcer nrglniea ahtt wyernaeh yfem.ls xh!t +1
therealslimshady  I t'nca ebreemmr ewerh I rdea hits but it kstuc htwi em, I ithnk ti asw a lcel bio bkoo +


You must be logged in to vote!

 +1  upvote downvote
submitted by mutteringly(34)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$379$49

sihT si omrf :oasbsm Mtdetau TCFR eeng (0Δ8F5 ao)mtiunt → mieosfdld teoprin → edvtceief iotpnre si eerdnita ni the hgruo sdpnleomaci riuctmuel ()REr ofr intaredagdo → -gtePdATa ohleicdr clnaehn si enabts on teh elcl uasercf of ihtailepel lcels ouourgtthh eth odyb .g(e., enttalinsi dna toeyrpirsra apee,ilthi etswa naglds, ocienerx ncepa,rsa erxcoeni lndgsa fo udcvtrprieeo n)osrga

unscramble the site ⋅ become a member$379$49


You must be logged in to vote!

 +0  upvote downvote
submitted by unknown001(9)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$379$49

LTRUA PLEM.IS

.thre1e ear myna nivsaart fo siyctc sibsfori so sith inteuosq si tno abotu phpayyt.hs fo CF

nt.o2ip of unoiqtes : wheer sdoe eptroni godilnf orccu ? ern)asw RER

  1. IN SIHT PEYT FO CF , fi noprite ontsi lfdoed reopplyr in RER lwli it go otu or iwll it ueactcamul ? rwsnea) ti wlli ucaetulmca in RRE.

TIP : FI UYO EKEP HGAREINESRC NO ARNTASVI FO FC, YUO AER ON A THPA TO NLSDESE DOMO

unscramble the site ⋅ become a member$379$49


You must be logged in to vote!

 +0  upvote downvote
submitted by blah_blah(1)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$379$49

fuh lleptw3g.nej=?cpi_aa;Hsp//hb&cNatoQBmhoyfasiwmntwoayu=unsI.lyhtvcGguoe/lXbe:w

unscramble the site ⋅ become a member$379$49


You must be logged in to vote!

 -1  upvote downvote
submitted by welpdedelp(270)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$379$49

_gn/n2hit7s5/n/1oh9M=3./d0_we_L:g9en0co_ssMn9?m138./5yi1_342e5ps/9.Pp2p51a/2TgCiob4vmtg3iH.082rF2slk221e

unscramble the site ⋅ become a member$379$49


You must be logged in to vote!

Must-See Comments from nbme24

seagull on Intestinal mucosa
tissue creep on Ask the roommate not to smoke in the apartment
drdoom on Adenosine
seagull on Increased serum testosterone concentration
atstillisafraud on Lamins
niboonsh on Only cookies are independently associated ...
atstillisafraud on Scar formation
lamhtu on Decreased adherence
drachenx on Damage to the rectovaginal septum
drdoom on Intestinal mucosa
azibird on Coronavirus
lsmarshall on Organic acid metabolism disorder
sympathetikey on Inhalant abuse
tea-cats-biscuits on Eosinophils

search for anything NEW!