,oS rfo omse o,nsaer utnesmenrattsrrio si otsihmneg veI' SAALWY udrtgelgs .twih.. rlbopbay eceuabs I tnsa'w htutga it wlel so nvere yelral elnrdea it, usjt dreanle ogunhe rof wvehrate xmae. I usjt fdonu sith obo trguohh CBIN dan tis SAITT!ANCF t'sI morf 0201 os higtm eb lod, btu it wsa egr.at ouY nca eahrsc uohrhgt the oobk adn nidf het hp.straec I tpyert ucmh ujts nwet utghrho lal of eht ientutatsornremr rh.ptace wtwbo:lk1mbsvgiK.0t.ns9Boo/.N//wn/p97ch.i/nh

yM nima l st-kmtuawyeaaGatea: = romaj xcoittyrea eaottrnnisumr.rte oTw pyste fo eero c:1srt)p b,ertoctamoip tsom fo iwchh ear pyisetranpc Gi chihw elsad to secdadere DNAM roetrecp itaciyvt and sirk fo exixiytciot,otci or yopnitpascts qG resocetrp ttha lead ot esceairn a+,N ,+K nda deeesadrc etgtumlaa aucsse ptiodlainearzo nda nersdciea M+g+ seamdlctpnie dan MNDA pteocrer tivyicat dna ksri of toeycixti,cixto nda 2) riiopoctno nhscneal ildugicnn MDAN nad PAaAaetMnik/ slanhn,ce wihhc lal aollw niiocnpcfes ncatoi x,ilfun but loyn ADMN aloswl +a+C inxlfu na(d lnyo in a taloveg ennpteedd annrem eftar etiufsficn idpotiraaznole has saldcpdie eth niohibrit +g+M noi ni het c.ahlne)n

ABGA nad ineyglc = biniyihrto ni.trsteseortanmru ) 1 A-GBAA nda AB-AGC = ocpotinior nscenalh thta aedl to luxef of C-,l dan pitesed ihst icgunas oldepaiin,otrza het orunen stlli tysas olbwe ersigtn tpeonlia.t GAB-AA gnniibd esti fro e,ruabrtbitas di,sestor A,BGA dan noxocritip = inisde rpeo of elannhc. G-AABA nigbind seti of ipozndeaeznesib = utosied fo orpe of .anhlecn 2) Ginylec enanhlc si a eryv ilasirm Cl- uflxe chlan.ne )3 BBGAA- is a ramcebttoiop aecnlnh ttah eaavstict iG niagedl ot drdaeeecs McPA ihcwh iteatacsv lxefuf K+ ehlcnsna and bihntiis ++aC lifxnu shenalcn ilandge to r.ipnrlepitoyaozha

cogneBii iasmen = onchiaeaemclst adnpeoim rind(inctaooo of dbyo oneemt,vm ,aewrdr o,oimtintav ),nnimcrfeeotre pnphrneineeori e(sel,p ukleanse,fws ,aninottte igdeenf aoehb,rvi irhnpenpiee we(stlo cntroctaoinne in S,)CN lups snnitoeor (l,psee ,ukseesnwalf sesnd,ipeor tay,xnie a)seuan and imansieth lsruaa(,o taotnte,ni yrael,gl ssueti aamgd,e nad aym eenfclnui oodlb nriab wf)lo. ,usvbOyilo all fo tihs is ni dodniita to cegdrenari omirsuoieastnnsnr adn ,hgtlfi ,thirfg dna ifgth resoep.sn

TAP adn ehrto spuiren = xiectrayot naom,itrssisn -adcsoeeerl ithw erhot l-slamelmecolu tri.annesormtrtsue nnAseiode tn'is aslsccylila ocisdednre a attnrerinrusetmo scebaeu it st'ni leerd/odsteasre ni ++aC npeeendtd nanr,em ubt deirdve fomr APT frbeeo nvgahi na eiatxorytc ptot.eianl

hcnteocleliAy = mjrao inotsranetetmrru ovneivdl ni srnmutiraononssei iav irumansc dna nnitiicoc sereoc.tpr

tpePdei rnetesrrtmousitan = lmoycmon edeeasrl sa rdeoppeitp reralg surresocpr taht aer vaceled by isfeicpc meeszny htta rewe ni eht meas trmutsrearnioent cesvlie oupn er.selea vieF spyte = uair/ntgb p,tedeips iodpio stepied,p iyutprita sdt,piep hycaiapohmlt isleenrga eonsm,hro dna hesto otn sici.lafdse lEsexpma = rcrueposr ahtt visge irse to asubtescn P upphispc,moa( eoot,enrcx and GIT nda rsaedeel fomr almls tdiraeem NSP C sfbrie tath snttarmi ianp dan atreumrptee i,onofaitmnr woelpfur yenh,spoeivt bnitidihe yb oopdii esp,ipt)de innnueokri A, eenoputpedir ,K adn ipoedeputren ,aamgm nda dpoiio ppiesedt liudcnngi tanpl slkoadali k(lie rnipom,he) tyhctines doiopi devvtis,iera and nhedpsino,r ,rhyndnoips and pin.keanlhse In grelena iidoop ipptesde rea aprdesesstn .(i.e gsaileaan hm,acsinm)e ovildnev in lcpxeom vbrseaoih aesxul( oaitnatctr, svge/sssvmugiiesiaerb ihoes,brva) dna pcdmleatii ho(tghu ont nieied)vfti in catcpsriihy .edsdsriro

aO,lvlre etrtnroinsmrutsea = ptye tp:yse collmulmselea- trriatesmsnt nda prien,topdseue rwhee l-mluocealsslem tetsnratirsm are reafts nad editmea ardip npatsyic nsrsosiitamn i.(e. aendorgn SNS lfgtttgirihf/fh/gih cikuq ,enr)osesp werhe sa puneeetsridop ln(goa ithw lobcigio misane dna mose amsll meoeucll irnes)tmttars rea roewls and miatede gadalr,u dolreongp rmntooniirasesn.su

oeSm utpiecr:s /d/rulb/etmiehucawnv/p_rdnitwonvattrke.testptimohfmhos_.dnaws.r/_irpu:epekeeou, 2nsscda1eiu8ortioae-5e3Ba-ce:belge/7o4bobsd//lat0-caA.BhPpn4ifTgheiw62w-8At01er4rstr/fia6rguea3l3s-r1aGgt2rw3tide9-pf0/0b6Rrfc/1n60/-repd-humgpps1., dan _meg-fteablU&t1g.3b0/nex:b-r-l.30t-pa9l/rbpw-d5-shw2feeedse2cin#hf=it6b.wseaw/-/aa7gn5autdldarg/i-6oe/i1h=4a;1dfx81g

oughT eusontqi.

ealcRl ahtt iMnaetnme zlsaehe(im'r dru)g si a DAMN eRrcpote Annoatgist ttah splhe vertenp eycciotixtxto yb ngcBkoil 2aC+ etynr. tTha's woh I mmeerber .hits

• )A GAAB-A srectepro lte l-C ni
• B) ineylGc is sued in eht lapnsi ocrd as an nioiitbryh nerto;rtasrnitmue oals lset -Cl in
• C dan )E aboteopcMtir gtluatmea eoecstprr era ipr-eotnG edopluc
• ,roeTrhefe the nlyo tnhig ttah cudlo etl aC2+ ni si ANDM rctepeosr

NDAM perocesrt ni shit aesc era gnieb uesd rof gonl ermt nttoanitpieo intwhi eht inrba nda uot fo lla fo htere cshcioe lnyo itsh oeertprc suse C+a

You can srawne by cspreso of ioiea.litnnm teCpi"mvteio tei"ricnoastn sekam ouy kihtn stulymortai .TN osCrs tuo GAAB adn el.cgnyi In het trexco so agt.aletum ooirbpcMteta luwdo amne ehst're dcnoes esegrsnsem iedolnvv nad teh tecroerp lwoud otn natrismt icm.alcu ecHne .AMND

udse in glno term etptoioannit ggl(e,nuaa eo)rmy,m Mya saol pyal a olre ni eneg titcinnrsproa ni nusnore

1) NDMA si a uGaleamtt peectorr )yepbu t2s MPAA si a btusype of MNAD ahtt is tyilliian divetacat by emattglua ee a3rlse) AMDN rsorteepc ear foudn earn MAAP rcrotespe utb rae otn tvadieact yb owl evlesl of ettamalgu lreeeas edu to a Mg ino og‘ncklb’i eth n h)eacl4n trneFque coiAnt letitpnoa g&t—; mlstoutanii fo AMPA tg;—& raioeelpsdz psot tcnpyisa rneoun g—&t; loeatvg ddneeetpn gM olckb of DNAM eretocrp merdevo 5 ) fnulxi fo Ca hhtorgu MNDA g&t;— csause eevn emor AAMP ctrsepeor ot be dnrsteei into teh abnemrem OTNE:( AAMP is svrspneioe ot aC dan ulga))te6 amt eacueBs eethr rea mreo orreptsce to erpndos to i,t hte ellc si orme sonvprseei to talgtmeua

lal the rehost a imocnniotvepte seinc they haev ycsiiseepicff(ticpci idla)ng,s DNAM is eht lyno neeslecnnee(covtih itteiovmcep poere)rtc, sah a dligna eits dan ca , na and .mgc.e.neh imepttiovec