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Retired NBME 23 Answers

nbme23/Block 2/Question#32 (reveal difficulty score)
A 2-year-old girl is brought to the physician ...
N-methyl-d-aspartate (NMDA) 🔍 / 📺 / 🌳 / 📖
tags: pharm neuro repeat

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 +19  upvote downvote
submitted by nwinkelmann(366)
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o,S rof eosm rea,son rrstutnermoniaset si monehgtis 'veI LAWSYA gltdeugsr h..w.it babrpyol cueaseb I tan'sw guhtat ti wlel so rnvee ylaerl lnaedre i,t stju adrneel ngheuo rof htaweerv mxae. I jstu onufd tsih oob rhthogu ICNB nad ist FANT!CISTA st'I morf 2001 so gmthi eb dol, ubt ti swa g.ater Yuo cna arcesh ruothhg hte okbo dan nfdi teh cp.aesrth I eyrttp cuhm sjut ewnt urohhtg lla of het nnetaertuirrsmto rehp.tac lc1n.:o.wwk/stK9ngbophn/N0/msti/9.wobB7v.i/h

My inma Gsamlttae- :ykuaeaatw = amroj ecattrioyx anertrritnt.emosu owT ysept fo ):1crsprteeo mtio,ertoabcp smto of whhci aer pnceaypirts Gi whhic sldae to dsedraeec NAMD ecpretor tavytcii dan srik fo xectyiot,tcoixii ro nppssocaytti Gq ectpersor tath edla to nircasee +a,N K,+ nad decaerdse geumtatla aucses padtialnoroezi adn iseaerdcn ++gM eesdnpamitcl dna DMNA eeprctro tvcatiyi dan krsi fo eoox,tcticxiiyt adn 2) otoroincpi nlacsnhe cindiungl DNAM nad kiAeaPt/MAan nn,claseh hicwh all alowl iecifsconpn ticnao xilnuf, but ylno NMDA wasoll +C+a unflxi na(d oyln in a tgoeval edpentned rnaenm ftare cinfefitus aroiitzelopnad has pacdiedls het ohirintib gM++ oni in het nea).clhn

AGAB dan lyginec = itibhrnoyi otrsrtnte.amsurine )1 AABG-A dna AA-BCG = nicrtoopoi nacneslh htat edal to luxef fo -lC, and ietdesp hsti giascnu il,apdoztoneiar het rnnueo llsit yatss ebwlo rsenitg .tinatelpo GABAA- iibndgn tsei fro tiabrute,bsar tdi,ssore B,AAG nda ixncoirtpo = ndisei opre fo ncnl.ahe AAGA-B ninbgdi site fo sopeneiazbinzed = etsdoiu of oerp fo anlc.hne )2 ycilGne clnhaen si a very ilmisar l-C efxlu anl.enhc 3) BB-AGA si a itobapcoertm lceanhn ttha vtceiatsa Gi dealnig ot aeddecers AMcP wihch tatcaives efuflx K+ hnslncea nda thnisiib aC++ iunxlf nacsnelh nladeig to npotrzaplreiohyia.

gnBecoii ianems = ametaoishlencc naomdpei cnatdoiiroon( fo byod enm,evtom wd,erar noiatm,ivot con,e)erifrntem hipieorrnnepne lp,se(e ,ksfluwnseea neiaotnt,t gfdieen arho,ivbe ipneereipnh o(lwest oanncecrotitn in C,)SN uspl irsnooetn lese(,p afssklew,eun e,eisdrspno i,eynaxt auaen)s nad tenhmisai uoarls,a( ,nntiateot agellry, iusset amage,d nda mya fnuelince oldob bnair .lo)wf i,lsobuOyv lla fo shti si in adidtoni ot rigedcearn eouinmrsistnsanor nad l,hgtfi ftgr,hi and tihgf n.eprsseo

APT nad troeh uesrinp = cttyaoerxi mrssonisan,ti srce-deeloa thiw hreot saulmlce-elmol etotmnstiar.snerur deAseoinn 'itsn ylcaslscial esinedcdor a oittrutesrnamenr uaecseb ti 'itsn tlro/sddaesreee in aC++ tneeeddpn mera,nn tub eiedrdv ormf PAT ofeebr vhniga na yxeractoit eaoittn.pl

iycolAhteclne = joram nrteeornuritsatm ivnedovl ni raesorsonntsniumi iav carnimsu dna ctnoiiinc eopsre.rct

ptedPie rmrrteseiustannto = lmoyomcn adrleees as pdiptepreo rrglea pucrrrseos atht are eedlvac by iisfcepc mseeynz taht reew in eth meas enrostetiarrtmnu cilevse ponu ee.aerls Five etsyp = t/uaingrb ,edesiptp poiido sedie,tpp ipyirutta spe,idtp lopthaiamcyh sigrealne somhorn,e dna hesot ton if.ldesiasc xplmasEe = rrupesroc taht igevs ires ot usatbencs P oaicppp,usmh( t,eocxnero dna GTI adn eedrsale mfor lalms emadiert SNP C iebfsr that istnarmt naip dan upreteramte nt,ornaiomif upewrflo invyoepste,h bihientdi yb doipio dtieps),pe nkneiruino ,A eoeirnutepdp K, adn tduoenrppiee gamm,a nda dooipi ipspetde gnciduiln antlp salklodia ike(l nhrpe,o)im tistechny podoii isa,dtveveri and odnhs,rienp hpod,rnnysi nda p.nekaelsihn nI aernelg ooipid idtepeps are asrnpdstese i.(e. asnalegai hnm,meis)ac ndvvolei ni moxcple hobvaeirs uelsax( ttacrnt,oia esgsivsvi/brsseemuagi r)ahesobv,i and dlmpeitcia (tughho ton )ditiefvien ni ptairhyscic drdierso.s

er,alvOl nnmsrrtteieotruas = ypte tepys: mlmeslcuaole-l tatsmrersitn adn ser,ouedenpitp eewhr ueslcelllsmm-ao mtntseirarts rae efatsr adn timeade rpdia aitnypcs snrstoanismi ..ei( agndneor SSN tfgthhhltrfgii//igf cqiku nes)so,pre hwree as itpndsruopeee (olnga hiwt cbogliio nsmiae nda moes lmasl locuemel tan)rsistrtem rae lwoers nda amteide rualdag, dorlneogp .ooriirtnassseumnn

moeS sceuirtp: ip.nerwtps_oosiurwehpanced.tfiueamdlt:h/beotpk/ir/mheurr_etvn_vdt./taswek/oumn, uenrBb-6a0e08s347ian/A1eAsG5/rw6iw4lh2gupie4agbrtcocw9-booihtp/-/datdc6fdR.har-ri-:ptaTt6euemre2c1B3b/e1rpf1sl//rglfoi0s13r-s-a.3sP2gad-0ftgee8pen0, adn gf-=7e.fahd-hse/./-_enle=pnr:soxdggwt1w/lt-dUt5icpd-e2bi64ama-drfaba19n&g/ia/tl#irex18aeu06b0tge1fbs;h3ale--3/b2.5ww

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sweetmed  shTi is .amzinag atknh uoy +
sweetmed  siTh si ng.amzia thank oyu +
paulkarr  h..W.ao +
brotherimodu  torhS eovid eemosno sodpte romf -N1B2ME serwn:as ?buwo=oQu.tww:/p4avwzvDtyemotH/hc2/cth.u-ws +6
dorischang  dniDt' nsfhii egdrina t,ish ubt it soklo amweose +3
kcyanide101  If yuo anawn retiw a tetx okob sutj ysa oll..so.. :) +

  • effect of glutamate antagonist on pt with acute cerebral infarction = targets NMDA receptor

  • decreases calcium entry into neurons = decreased excitotoxicity = promotes recovery from acute cerebral infarction.


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 +19  upvote downvote
submitted by sympathetikey(1600)
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ughTo o.iteunqs

Raellc htat eteainnMm zmirhee('asl rg)ud si a DNAM opetcerR snoAaigtnt ahtt eplhs erepnvt oxyetcctoitix yb koBngcli 2a+C ntyre. 'htTsa hwo I meebrmer sh.ti

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veryhungrycaterpillar  wtj1rc9u/.:sworrnws//egootp9h.oe0c0ht3i.n/tt/n/stGe ar ltelit rad,e dan itsh is eht aeppr yhte pterty cmuh ebdsa this notqeuis o.n +
veryhungrycaterpillar  enikdL eht worgn p.arpe tanMe ot likn iths o:en 5ispsPln/w.c6.m7trch.Cpg./6l/bain0vei//2httcw/:mMn8ow +

a picture for better understanding https://2e.mindsmachine.com/asf04.02.html

^ link is dead :( (they published a 3/e) but here is the re-route to the new site if anyone wants to dig in https://learninglink.oup.com/access/watson3e-student-resources

+/- drdoom(1206)

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 +4  upvote downvote
submitted by spow(50)
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  • A) A-AGAB sterprceo let -lC in
  • B) cGenliy is seud in eth nspila droc as an riobiytnhi nuoeiret;rtasmtnr oasl stle C-l ni
  • C nad E) Maotcbpierto utgetaaml tcsoerper rea rioG-npet dcepolu
  • ehr,eofrTe teh nloy gtnih atht loucd elt a+2C in si NAMD oecretprs
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thotcandy  roniacgcd ot itsh, TH35 is an ino hnnealc l(aiynm Na nda ,K btu moes Ca) so atht saw dinak yeff imo +


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 +3  upvote downvote
submitted by lfsuarez(160)
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DAMN ecsetprro ni tihs eacs ear benig esud ofr olgn rmte ntetoapionti hniitw het nbrai dan uot of all fo rteeh schcioe oynl htsi tcperero essu +aC

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 +1  upvote downvote
submitted by chasingdreams101(4)
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I pecidk NMDA becuaes tsi’ tlosui,mryat tbu is ehtre nay ereepd nearso fro ih?st

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tea-cats-biscuits  Teh Q si aulytcla gsaink hwcih fo teh orpescert use +Ca ,soin dan of the iehcosc evgni only MNDA etocrepsr do o.s +32


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 +1  upvote downvote
submitted by adong(144)
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ouY can nrwsea by cspsreo of amnie.ioinlt ii"Cemeopttv acesniiro"tnt esamk you inkth rtayotuimls .NT soCsr uto AGBA nad ylgince. nI eth toercx os tu.aamelgt pMboeitotcra wodul mean ehsetr' scndeo ssneeemrsg envdvloi and teh ptceroer lwduo ton msanttri mclia.uc cHene N.MDA

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 +1  upvote downvote
submitted by an1(114)
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esud ni ongl etmr npteotoaitni g,eglaau(n e)mm,oyr yMa laso lyap a orel in eeng tiraipctornns in ornensu

1) DNAM si a luaGmatet oprceret espb2tuy) PAMA is a psyutbe fo ANMD ahtt is inatliiyl vataedict by gaumtalet )er 3eales DAMN cotpersre rea dounf arne PAAM trerecspo ubt rae otn vaattdeci by olw velels fo uamlatgte laseeer ude to a gM oni lcikn‘og’b het a lnc)hne4 tnqeeuFr intcoA peliattno —;g&t utiotnimals fo APMA —;> pesaorzdlie ospt nipsatyc oenurn ;—> ovelgta eepneddtn gM lcbko fo NMAD tpcoeerr vdmeore )5 ixufln fo aC uthhrgo DAMN t—g&; cueass nvee omre APMA preceotrs ot be riseedtn onit the abrmeemn TO:NE( APMA si opveersnsi ot aC dan age6)mt)lta u ecsueaB etehr rea mroe teseocrpr ot repsndo to it, teh elcl si emor nsoipveser to ttugealma

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 +0  upvote downvote
submitted by zpatel(36)
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all eht orseht a mcintentpvooei cenis ehyt vaeh cfcsiptiiiyif(cepsce n,gsl)adi ADMN is the ylon (eeenitocsneclehvn temetcpvioi tcre)poer, ash a anilgd seti and ca , na nda .hn.m.ecge ttpcmeeovii

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hello  eht suiqeont ssya ipeotvmtice steinanocti,r i inhtk shit si tnreeidff ofmr cimtpvoetie bdgnnii. +


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